Module 2.6 Blood Cells and Hematopoietic system

Question 1

What kind of tissue is blood

Answer 1

Connective tissue

Question 2

Makeup of blood

Answer 2

55% plasma
<1% Buffy coat (WBC’s and Platelets
45% erythrocytes ( whole blood)

Question 3

Albumin

Answer 3

54% of plasma proteins
Maintains oncotic pressure
Carrier for some substances

Question 4

globulins

Answer 4

38% of plasma proteins
Alpha - carries bilirubin and steroids
Beta - Transport Iron and Copper
Gamma Globulins - antibodies of the system

Question 5

Fibrinogen

Answer 5

7% of plasma proteins

Converted to fibrin in clotting process

Question 6

Serum

Answer 6

Plasma WITHOUT fibrinogen or other clotting factors

Question 7

Gold tube function

Answer 7

substance causes clotting, whats left is serum

Question 8

What important enzyme is carried in the cellular fluid of RBC’s

Answer 8

Carbonic anhydrase (important for acid base balance)

Question 9

Neutrophils

Answer 9

50-60% of WBC’s
Granulocyte
First to arrive

Question 10

Origin and life path of Neutrophils

Answer 10

originate from myeloblasts in the marrow.

Stay in blood 1-2 days, then 4-8 days in tissue before death

Question 11

lifespan of RBC’s

Answer 11

128 days

Question 12

Eosinophils

Answer 12

1-3% of WBC’s
Granulocyte
Increase in allergic reactions and PARASITIC infections

Question 13

Basophils

Answer 13

0.3-0.5% of WBC’s
Granulocyte
Contain Heparin and Histamine
Become MAST cells when they move into tissue

Question 14

Lymphocytes

Answer 14

20-30% of WBC’s
NOT Granulocytes
B, T, and NK cells

Question 15

Monocytes and Macrophages

Answer 15

3-8% of WBC's 
NOT Granulocytes
Activate lymphocytes
Antigen presenter cells
Survive months to years in tissues.

Question 16

Thrombocytes

Answer 16

Platelets
last 8-9 days in circulation
(Pt’s need to stop using aspirin for long enough to replace all affected platelets before surgery)

Question 17

Hematopoiesis

Answer 17

Formation of blood components

Question 18

Cytokine role in Hematopoiesis

Answer 18

Hormone-like growth factors

Question 19

Lymphoid cell line gives rise to

Answer 19

T-Cells
B-Cells > Plasma Cells
NK-Cells

Question 20

Myeloid Stem Cell line gives rise to

Answer 20

Anything that isn’t a T, B or NK cell or plasma cell

Question 21

Colony Stimulating Factors

Answer 21

Erythropoietin (EPO) - RBC production

Thrombopoietin - stimulates platelet differentiation

X-CSF - X production

Question 22

Where does Erythropoietin come from

Answer 22

the kidneys

Question 23

Erythrocyte sedimentation rate (ESR) test

Answer 23

Non-specific

Used to follow effects of chronic diseases