Module 1 Unit 3 - Thalamus Flashcards
What is the only sensory input not involving the thalamus
olfactory. mediated through the olfactory bulb which provides input to the thalamus
Thalamus roles
Auditory, visual, all sensory pathways except olfactory.
Emotions
Short Term Memory
Spinothalamic tract
input/sensory (Dorsal/posterior)
Corticospinal tract
output/motor (ventral/anterior)
Anatomical position of Sympathetic NS innervation on the spine
Thoracolumbar
Anatomical position of Parasympathetic NS innervation on the spine
Cervical and Sacral
NT for all preganglionic gap junctions regardless of system
ACh (nicotinic receptor)
NT for postganglionic neurons of the Sympathetic NS? Exception?
Norepi and Epi. Exception is sweat glands which also use ACh (muscarinic receptor)
NT for postganglionic neurons of the Parasympathetic NS?
ACh (Muscarinic receptors)
What is Atropine
Muscarinic cholinergic receptor blocker
Muscarinic Cholinergic Receptor
post ganglionic parasymp. fibers and sweat glands in sympathetic NS
Nicotinic Cholinergic Receptor
autonomic ganglia and end plated skeletal muscle
ACh effect on cholinergic receptors
Excitatory to most EXCEPT heart and lower esophagus where they are inhibitory. (Why we give atropine in CODES. stimulates the heart,)
Catecholamines (sympathetic hormones) are derived from
Tyrosine (essential amino acid)
3 Catecholamines
Dopamine
Norepi
Epi
How are Catecholamines mediated?
Vesicle mediated
How are Catecholamines cleared
Reuptake for later use or degraded by COMT and MAO
Norepinephrine effects
Potent excitatory activity and low inhibitory activity
Epinephrine effects
Potent excitatory activity and inhibitory activity
Alpha vs Beta Receptors
Alpha is excitatory, Beta is Inhibitory
a1 receptor
post synaptic sites in smooth muscle - vasoconstriction
a2 receptor
presynaptic. INHIBIT release of Norepi. Mostly in CNS. Influences BP.
B1 receptor
Primarily in heart. causes increased HR and contractility (seems counter intuitive to inhibitory nature. trust)
B2 receptor
Primarily in bronchioles. Relaxation of smooth muscles, bronchodilation.