Module 1 Unit 3 - Endocrine Control Flashcards
Posterior Pituitary hormones
Oxytocin and ADH (RELEASED FROM POSTERIOR PITUITARY, MADE IN HYPTHALAMUS)
Anterior Pituitary hormones
TSH, ACTH, Prolactin, GH, Gonadotropins (FSH and LH) (MADE IN PITUITARY)
Where are vesicle mediated hormones made? Where are they stored until release?
Rough ER, Cytoplasm of the cell
Where are non-vesicle mediated hormones made? Which hormones are these?
Smooth ER, Steroids
Which hormones are carrier bound in the blood stream?
Thyroid hormones and steroids
How does carrier protein binding correlate to half life
positive correlation. Higher binding ratio means longer half life
Up-regulation
production of more hormone receptors to increase sensitivity in response to low hormone levels
Down-regulation
Reduce number of hormone receptors to decrease sensitivity
Lipid soluble hormones
enter cell by passing membrane
Non-lipid hormone
cannot cross. use second messenger system
What is the non steroid hormone that is the exception to the rule and binds to an intracellular receptor?
Thyroid hormone. It has a transporter molecule
Somatotrophs
cells in anterior pituitary that make GH
Primary Disorder
origin in target organ
Secondary Disorder
Pituitary origin
Tertiary Disorder
hypothalamus origin