Module 17 ch. 29 Flashcards
Oral Inflammation has been linked to several conditions including _____ and ___
stroke
heart disease
Increased _____ associated with diabetes can make a patient more susceptible to Perio?
Inflammation
What are the 3 benefits of using Dentrifices?
Preventative
Therapeutic
Cosmetic
What 2 substances in toothpaste prevents caries?
Xylitol
Fluoride
Fluoride can enhance ______ of noncavitated caries?
remineralization
What agents in toothpaste are used to reduce biofilm formation?
Triclosan
Zinc Citrate
Stannous Fluoride
An Antimicrobial agent is a chemical that is ____
bacteriostatic/bacteriocidal
The ability of an agent to bind to the pellicle, etc and can be released over an extended period of time has good _____?
Substantivity
_____ is the primary agent in toothpaste that has shown efficacy in reducing gingival inflammation
Triclosan
What is the best ingredient in toothpaste for reduction of dentin hypersensitivity?
5% Postassium Nitrate
What agent in toothpaste deals with tartar-control?
Pyrophosphate salts
Zinc Salts
Cosmetic effects of toothpaste are based on the ability to _____and ____?
remove extrinsic stain
deliver a bleaching agent
Halitosis can be temporarily removed by inhibiting the production of _____?
VSC
VSC stands for
Volatile Sulfur Compounds
What ingredient in toothpaste has a foaming action?
Detergent
A polishing agent or (______) is used in toothpaste to leave a smooth tooth surface.
abrasive
Binders or _______ are used to prevent separation of _____ and ____ and to _____ the formula.
thickeners
solid
liquid
stabilize
Moisture Stabilizers are called _____ and are used to retain ___ and prevent _____ of toothpaste
humectants
moisture
hardening
The purpose of a preservative in toothpaste is to prevent ____ and prolong ____
bacterial growth
shelf life
What are the 6 actions of dentrifices?
Anti-caries biofilm gingivitis calculus halitosis sensitivity
At eruption of first tooth you should use a ____ of toothpaste. At 2-5 yrs old you can use a _____ size of toothpaste
smear
pea-sized
Mouth-rinses can be classified as ____, ____,or ______
preventative
cosmetic
therapeutic
Rinsing can deliver an agent less than _____mm into the sulcus/pocket.
2
Patients rinse before tx to decrease?
number of microorganisms in mouth
Stannous Fluoride interferes with _______ giving it an antimicrobial effect
cell metabolism
Sodium Fluoride is a ____ agent that inhibits ____ and enhances _____
cariostatic
demineralization
remineralization
Chlorhexidine rinses are bacterialcidal by causing?
cell lyses
The substantivity of chlorhexidine rinses is?
8-12 hr
______ is a broad spectrum agent effective against gram-neg and gram-pos bacteria.
Triclosan
Listerine is an example of a _____?
*causes burning
phenolic-related essential oil
What is the most common oxygenating agent?
10% carbamide peroxide
1.5%hydrogen peroxide
Prolonged use of oxygenating rinses has resulted in?
gingival irritation/delayed tissue healing
What agents in mouth rinses reduces halitosis?
Oxidizing
What are the characteristics of an effective chemotherapeutic agent?
Nontoxic No absorption Substantivity Bacterial Specificity Low drug resistance
Zerostomia is worsened by using what type of mouth rinse?
alcohol based
Mouth rinses are contraindicated for kids under age
6
The _____ ensures the safety and efficacy of medical and dental drugs, equipment, and devices that affect living tissue.
FDA
Do rinses and dentrifices have to get FDA approval?
YEs
Pre-clinical phase of FDA clearance studies ___ for ____ purpose
animals
safety/toxicity
Phase 1 of FDA clearance studies ______ to determine ______
small group
dosing/safety
Phase 2 of FDA clearance studies ______ to provides_____
larger group (placebo test) further safety data
Phase 3 of FDA clearance studies ______ to identify ______
large group (test efficacy) side effects
Phase 4 of FDA clearance studies _____ to continue to ______
clinical trials on the market
measure long-term benefits and risks
