Module 11: Intro to Macromolecules Flashcards
examples of electrically charged side chains; hydrophilic
aspartic acid (negatively charged)
glutamic acid (negatively charged)
lysine (positively charged)
arginine (positively charged)
histidine (positively charged)
these account for more than 50% of the dry mass of most cells
proteins
molecules containing ____________________ have the potential to react with water, releasing energy
phosphate groups
these are the one class of large biological molecules that do not form polymers
lipids
these can undergo mutarotation (C1 - anomeric carbon)
monosaccharides
form nonpolar covalent bonds
hydrocarbons
examples of sugar
glucose
fructose
sucrose
these stores, transmits, and helps express hereditary information
nucleic acids
polymers are disassembled to monomers by?
hydrolysis
two types of nucleic acids
deoxyribonucleic acid
ribonucleic acid
these are constructed from two types of smaller molecules: glycerol and fatty acids
fats
a cyclic form of monosaccharides that is a five-membered ring
furanose ring
humans and other mammals store their fat in?
adipose cells
a nucleic acid made of monomers called nucleotides
DNA
it removes a water molecule, forming a new bond
dehydration
it serves as fuel and building material
carbohydrates
hemiacetals and hemiketals can react with alcohols in the presence of acid to form?
acetals and ketals
these are stereoisomers of a cyclic monosaccharide that differ in the position of the OH group at the hemiacetal carbon
anomers
it is the most common monosaccharide
glucose
examples of polysaccharides
starch
cellulose
these also cushions vital organs and insulates the body
adipose tissue
it also provides structural support for the cell walls of many fungi
chitin
these provide a fibrous framework in animal connective tissues
collagen and elastin proteins
examples of polar side chains; hydrophilic
serine
threonine
cysteine
tyrosine
asparagine
glutamine
these may reinforce the protein’s structure
disulfide bridges
this is the protein of milk and is the major source of amino acids for baby mammals
casein
this is determined by interactions between R groups
tertiary structure
these are made of DNA, a nucleic acid made of monomers called nucleotides
genes
the most biologically important lipids are?
fats, phospholipids, and steroids
another structural polysaccharide, is found in the exoskeleton of arthropods (crunch!)
chitin
name of the amino end in a unique linear sequence of amino acids
N-terminus
the amino acid sequence of a polypeptide is programmed by a unit of inheritance called?
gene
examples of disaccharide
maltose
sucrose
lactose
it passes through the digestive tract as insoluble fiber
cellulose
the linear form of starch
amylose
these results when two or more polypeptide chains form one macromolecule
quaternary structure
it has the OH group on the stereogenic center farthest from the carbonyl on the right in a Fischer projection (like D-glyceraldehyde)
D-sugar
these are classified by the number of carbons in the carbon skeleton
monosaccharides
DNA is a nucleic acid made of monomers called?
nucleotides
it consists of an organic molecule called adenosine attached to a string of three phosphate groups
ATP
functions as selective acceleration of chemical reactions
enzymatic proteins
these are organic molecule protein monomers with carboxyl and amino groups
amino acids
protein synthesis occurs on?
ribosomes
it is a fibrous protein consisting of three polypeptides coiled like a rope
collagen
_______________________________ in hair proteins maintains the curliness or straightness of hair
cross-linking of cysteines
what are the polymers of sugars
cellulose
starch
carbohydrates containing a hemiacetal are in equilibrium with an acyclic aldehyde, making them?
reducing sugars
it is an important source of energy for cellular processes
ATP
open form of D-glucose
D-glucopyranose
transport of substances
transport proteins
name of the carboxyl end in a unique linear sequence of amino acids
C-terminus
it is an important steroid
cholesterol
this directs synthesis of messenger RNA (mRNA) and, through mRNA, controls protein synthesis
DNA
it is the breaking down of polymer
hydrolysis
these can exist in both open or closed form
monosaccharides
it is a reaction that is the reverse of the dehydration reaction
hydrolysis
monosaccharides with a ketone carbonyl group at C2 are called?
ketoses
the branched form of starch
amylopectin
these are acetals, so they are not in equilibrium with any acyclic aldehyde, making them nonreducing sugars
glycosides
the simplest carbohydrates are called?
monosaccharides
what are the cyclic forms of monosaccharides?
pyranose
furanose
it is polar as a result of the electrons spending more time near the electronegative oxygen atom
ethanol
it acts as a base
glycine
these are lipids characterized by a carbon skeleton consisting of four fused rings
steroids
these differ in their properties due to differing side chains, called R groups
amino acids
these are linked by peptide bonds
amino acids
each nucleic acid is made of monomers called?
nucleotides
it is a three-carbon alcohol with a hydroxyl group attached to each carbon
glycerol
these have molecular formulas that are usually multiples of carbo-hydrate
monosaccharides
four classes of large biological molecules
carbohydrates
lipids
protein
nucleic acids
these are unbranched polymers built from the same set of 20 amino acids
polypeptides
synthesis of disaccharides
- dehydration reaction in the synthesis of maltose
- dehydration reaction in the synthesis of sucrose
it consists of a carboxyl group attached to a long carbon skeleton
fatty acid
it occurs when two monomers bond together through the loss of a water molecule
dehydration reaction
it adds a water molecule, breaking a bond
hydrolysis
storage of amino acids
storage proteins
it contains more than two sugars linked, have storage and structural roles
polysaccharides
arrangement of _________________ in male and female sex hormones affects their shape and function
methyl groups
The _____________ and ___________________ of functional groups give each molecule its unique properties.
number, arrangement
monosaccharides with an aldehyde carbonyl group at C1 are called?
aldoses
these are the components of organic molecules that are most commonly involved in chemical reactions.
functional groups
dehydration synthesis
peptide bonds
Tertiary structure is determined by interactions between R groups – these include actual ionic bonds and strong covalent bonds called?
disulfide bridges
a _____________ protein is biologically inactive
denatured
the loss of a protein’s native structure is called?
denaturation
these ranges in length from a few to more than a thousand monomers
polypeptides
these are hydrophobic because they consist mostly of hydrocarbons, which form nonpolar covalent bonds
lipids
these are a diverse group of hydrophobic molecules
lipids
these are large molecules composed of thousands of covalently bonded atoms
macromolecules
the iron-containing protein of vertebrate blood, transports oxygen from the lungs to other parts of the body
hemoglobin
these are classified by the location of the carbonyl group
monosaccharides
carbohydrates containing a hemiacetal are in equilibrium with an _________________, making them reducing sugars
acyclic aldehyde
it is the primary energy-tranferring molecule in the cell
ATP
molecular structure and function are?
inseparable
what do you call the polymers that are composed of many sugar building blocks
polysaccharides
these are the major component of all cell membranes
phospholipids
it has the OH group on the stereogenic center farthest from the carbonyl on the left in a Fischer projection (like L-glyceraldehyde)
L-sugar
these determines protein structure
- alterations in pH
- salt concentration
- temperature
- other environmental factors
it is a component in animal cell membranes
cholesterol
this provides directions for its own replication
DNA
it is the protein of egg white and used as an amino acid source for the developing embryo
ovalbumin
it is a biologically functional molecule that consists of one or more polypeptides
protein
a cyclic form of monosaccharides that is a six-membered ring
pyranose ring
addition of a ___________________ to DNA, or to molecules bound to DNA, affects the expression of genes
methyl group
examples of nonpolar side chains; hydrophobic
glycine
alanine
valine
leucine
isoleucine
methionine
phenylalanine
tryptophan
proline
it acts as an acid
acetic acid
it is the protein of hair, horns, feathers, and other skin appendages
keratin
these distinguish living matter and are all composed of carbon compounds
proteins, DNA, and carbohydrates
it can form hydrogen bonds with water molecules, helping dissolve organic compounds such as sugar
ethanol
functions as a support
structural proteins
functions as protection against diseases
defensive proteins
what do you call an open form of monosaccharides
Fischer projection
Fats are constructed from two types of smaller molecules namely?
glycerol and fatty acids
what do you call the closed form of monosaccharides
Haworth projection
these functions include structural support, storage, transport, cellular communications, movement, and defense against foreign substances
protein
this is an inherited blood disorder, results from a single amino acid substitution in the protein hemoglobin
sickle-cell disease
these can react with alcohols in the presence of acid to form acetals and ketals
hemiacetals and hemiketals