MOD 3 Flashcards
apoptosis
cell death caused by the genetic programming of the cell to eliminate damaged cells
asphyxiation
cellular deprivation of oxygen; suffocation.
atelectasis
an airless state in which the alveoli are collapsed.
cardiomyopathy
Enlargement of the heart.
compensated shock
a state of inadequate cellular perfusion in which the body can make adjustments to maintain perfusion to the vital organs, but at the cost of decreased circulation and oxygenation of the peripheral tissues.
decompensated shock
a state of inadequate cellular perfusion in which the body can no longer provide circulation of an adequate amount of oxygenated blood to the vital organs.
hyperpyrexia
an extremely high fever, above 41.1 degrees Celsius or 106 degrees Fahrenheit.
ischemia
severely diminished or absent blood flow to tissues.
ischemic phase
the phase of shock in which both the precapillary and postcapillary sphincters constrict to divert blood flow away from the peripheral tissues and gastrointestinal system.
lactic acid
a chemical formed from pyruvate in anaerobic metabolism; the cause of acidosis in shock.
metabolic acidosis
a decreased blood pH and decrease in bicarbonate level in the blood.
pyruvate
the initial substance formed in the anaerobic phase of cellular metabolism that, in the presence of oxygen, is then converted to acetyl coenzyme A for use in the Krebs cycle for further ATP production. In the absence of oxygen, pyruvate is converted to lactic acid.
stagnant phase
the phase of shock in which the precapillary sphincter fails, allowing blood to enter the microvasculature. The postcapillary sphincter remains closed, causing blood to pool in the capillary beds, where it collects lactic acid and where microscopic blood clots are formed.
ventilation–perfusion (VQ) mismatch
a condition in which either pulmonary circulation or alveolar ventilation is impaired.
washout phase
the phase of shock in which both the precapillary and postcapillary sphincters have failed and the blood that had stagnated in the capillary beds, along with lactic acid and microscopic blood clots, reenters the circulation.