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2nd Year - 1st Sem > (Midterms) PCOG Lec Quiz 2 > Flashcards

(Midterms) PCOG Lec Quiz 2 Flashcards

1
Q

Secondary metabolites of carbohydrates along with gum and mucilages

A

Glycosides

Plant constituents that produce sugar as products of hydrolysis

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2
Q

Glycosides AKA?

A

Sugar Ethers

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3
Q

What is Glycoside composed of?

A

Glycone and Aglycone

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4
Q

These are regulatory, protective, and sanitary compounds

A

Glycosides

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5
Q

Sugar component of the Glycoside

A

Glycone

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6
Q

NON Sugar component of the Glycoside

A

Aglycone

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7
Q

Component of Glycoside that is the common denominator

A

Glycone

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8
Q

Component of Glycoside that is the basis of classification

A

Aglycone

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9
Q

Inactive component of Glycoside (No Pharmaceutical Action)

A

Glycone

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10
Q

Active component of Glycoside (Has Pharmaceutical Action)

A

Aglycone

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11
Q

What is Glycone composed of?

A

Sugar moiety

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12
Q

What is Aglycone composed of?

A

Lactone moiety and Steroid nucleus (CPPP: Cyclopentanoperhydrophenanthrene)

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13
Q

Other name of Aglycone

A

Genin

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14
Q

What test is used to determine Glycones?

A

Keller Kiliani Test

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15
Q

What test is used to determine Aglycones?

A

Liebermann-Burchard and Salkowski Test

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16
Q

What is the MOA of Cardiac Glycosides?

A

Inhibits the NA/K ATPase Pump

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17
Q

Where does the N/K ATPase Pump occur

A

Myocytes (Cardiac Muscles)

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18
Q

What is the goal of Cardiac Glycosides

A

To keep the Calcium in the cell

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19
Q

Two types of Cardiac Glycosides

A

Cardenolide and Bufadienolide

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20
Q

Which is more common in the 2 types of Cardiac Glycoside

A

Cardenolide

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21
Q

Which has optimum activity in the 2 types of Cardiac Glycosides

A

Cardenolide

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22
Q

Which is less common in the 2 types of Cardiac Glycoside

A

Bufadienolide

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23
Q

Which has less activity in the 2 types of Cardiac Glycosides

A

Bufadienolide

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24
Q

C,24,6 - membered lactone ring

A

Bufadienolide

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25
Q

C,23,5 - membered lactone ring

A

Cardenolide

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26
Q

Water Soluble: Digoxin or Digitoxin

A

Digoxin

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27
Q

Lipid Soluble: Digoxin or Digitoxin

A

Digitoxin

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28
Q

Less Toxic: Digoxin or Digitoxin

A

Digoxin

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28
Q

A digoxin common in hospitals for rapid initial dosing

A

Deslanoside

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28
Q

More Toxic: Digoxin or Digitoxin

A

Digitoxin

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29
Q

Absorbed: Digoxin or Digitoxin

A

Digitoxin

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30
Q

Common Brand name of Digoxin

A

Lanoxin

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30
Q

Excreted: Digoxin or Digitoxin

A

Digoxin

31
Q

Common Brand name of Digitoxin

A

Reslanoside

32
Q

Scientific name of Foxglove/Purple Foxglove

A

Digitalis purpurea

33
Q

Scientific name of Grecian Foxglove

A

Digitalis lanats

34
Q

What type of glycoside is G-strophanthin

A

Rhamnose Glycoside

34
Q

Toxic component of the Strophanthus plant

A

G-Strophanthin

35
Q

G-Strophanthin is also known as?

A

Ouabain

36
Q

Used for preparation of ouabain injection

A

G-Strophanthus

37
Q

30% of Fixed oil, the bases trigonelline and choline, resin and mucilage

A

Strophanthus kombe (K-Strophanthus)

38
Q

4-8% of Ouabain

A

Strophanthus gratus (G-Strophanthus)

39
Q

Toxic moiety that should not be a constituent of Squill

A

Red Moiety

39
Q

What is Red Moiety used for

A

Used more in rodenticides

40
Q

Which among the 3 consituents of Black Hellebore have a digitalis-like action

A

Helleborein, Hellebrin

41
Q

3 Constituents of Black Hellbore

A
  1. Helleborin
  2. Helleborein
  3. Hellebrin
42
Q

Bufadienolide analogue of Strophanthin

A

Hellebrigenin

43
Q

What is 20 times more powerful than Helleborein

A

Hellebrin

43
Q

Hellebores:

White and Green are?
Black is?

A

White and Green are cardiac depressant
Black is cardiac stimulant

44
Q

Bufadienolide or Cardenolide?

Squill

A

Bufadienolide

44
Q

Bufadienolide or Cardenolide?

Red Squill

A

Bufadienolide

44
Q

Bufadienolide or Cardenolide?

Indian Squill/Urginea

A

Bufadienolide

44
Q

Bufadienolide or Cardenolide?

Black Hellebore Rhizome

A

Bufadienolide

45
Q

Bufadienolide or Cardenolide?

Digitalis leaf

A

Cardenolide

45
Q

Bufadienolide or Cardenolide?

Strophanthus

A

Cardenolide

45
Q

Bufadienolide or Cardenolide?

Oleander

A

Cardenolide

45
Q

Bufadienolide or Cardenolide?

Convallaria

A

Cardenolide

45
Q

Family of Convallaria majalis

A

Liliaceae

45
Q

What properties do Convallaria have

A

Cardioactive properties, which are similar to those of digitalis but much less cumulative

45
Q

Where are Convallaria collected from?

A

Aerial parts, rhizomes, and roots

46
Q

What does Convallatoxin give after getting hydrolysed

A

Strophanthin and Rhamnose

46
Q

Contains minor cardenolides, 40 glycosides with nine different aglycone

A

Convallaria majalis

46
Q

A glycoside of the Convallaria seeds

A

Convalloside

47
Q

When Convalloside is acted on what does it yield

A

Convallatoxin and dglucose

48
Q

What is extracted from leaves of Convalloside

A

flavonoids

48
Q

From the hydrolysis of glycose, cymarose and periplogenin

A

Periplocin

49
Q

What is extracted from roots of Convalloside

A

Saponin, 3 Sugar chains at C1,C2,C7

49
Q

Color of anthraquinone derivatives?

A

Orange

49
Q

From the hydrolysis strophanthidin and digtoxose

A

Erysimin

49
Q

What is appropriate solvent of Chrysarobin

A

Hot Benzene

49
Q

Is Anthraquinone a sugar or non sugar?

A

Nonsugar (Algycone)

50
Q

ID Test of Anthraquinone

A

Bontrager Test

50
Q

Cascarosides A and B?

A

Barbaloin

50
Q

What is the use of Anthraquinone Glycosides?

A

Cathartics, EXCEPT Chrysarobin

51
Q

Cascarosides C and D?

A

Chrysaloin

52
Q

Drug name of Frangula Buckthorn Black

A

Movicol

Component: Frangula and (Sterculia) Karaya

52
Q

Can be a treatment for burns

A

Aloe

53
Q

At what % can Aloe be a treatment

A

2%

54
Q

What is the active constiuent of Aloe

A

Barbaloin

55
Q

Can cause skin change or Keratolytic

A

Chrysarobin

56
Q

Chrysarobin is toxic in nature, so what was the semisynthetic that replaced Chrysarobin?

A

Anthralin

2nd Year - 1st Sem (20 decks)

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