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2nd Year - 1st Sem > (Midterms) PCOG Lec Quiz 2 > Flashcards

(Midterms) PCOG Lec Quiz 2 Flashcards

1
Q

Secondary metabolites of carbohydrates along with gum and mucilages

A

Glycosides

Plant constituents that produce sugar as products of hydrolysis

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2
Q

Glycosides AKA?

A

Sugar Ethers

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3
Q

What is Glycoside composed of?

A

Glycone and Aglycone

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4
Q

These are regulatory, protective, and sanitary compounds

A

Glycosides

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5
Q

Sugar component of the Glycoside

A

Glycone

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6
Q

NON Sugar component of the Glycoside

A

Aglycone

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7
Q

Component of Glycoside that is the common denominator

A

Glycone

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8
Q

Component of Glycoside that is the basis of classification

A

Aglycone

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9
Q

Inactive component of Glycoside (No Pharmaceutical Action)

A

Glycone

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10
Q

Active component of Glycoside (Has Pharmaceutical Action)

A

Aglycone

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11
Q

What is Glycone composed of?

A

Sugar moiety

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12
Q

What is Aglycone composed of?

A

Lactone moiety and Steroid nucleus (CPPP: Cyclopentanoperhydrophenanthrene)

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13
Q

Other name of Aglycone

A

Genin

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14
Q

What test is used to determine Glycones?

A

Keller Kiliani Test

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15
Q

What test is used to determine Aglycones?

A

Liebermann-Burchard and Salkowski Test

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16
Q

What is the MOA of Cardiac Glycosides?

A

Inhibits the NA/K ATPase Pump

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17
Q

Where does the N/K ATPase Pump occur

A

Myocytes (Cardiac Muscles)

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18
Q

What is the goal of Cardiac Glycosides

A

To keep the Calcium in the cell

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19
Q

Two types of Cardiac Glycosides

A

Cardenolide and Bufadienolide

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20
Q

Which is more common in the 2 types of Cardiac Glycoside

A

Cardenolide

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21
Q

Which has optimum activity in the 2 types of Cardiac Glycosides

A

Cardenolide

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22
Q

Which is less common in the 2 types of Cardiac Glycoside

A

Bufadienolide

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23
Q

Which has less activity in the 2 types of Cardiac Glycosides

A

Bufadienolide

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24
Q

C,24,6 - membered lactone ring

A

Bufadienolide

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25
C,23,5 - membered lactone ring
Cardenolide
26
Water Soluble: Digoxin or Digitoxin
Digoxin
27
Lipid Soluble: Digoxin or Digitoxin
Digitoxin
28
Less Toxic: Digoxin or Digitoxin
Digoxin
28
A digoxin common in hospitals for rapid initial dosing
Deslanoside
28
More Toxic: Digoxin or Digitoxin
Digitoxin
29
Absorbed: Digoxin or Digitoxin
Digitoxin
30
Common Brand name of Digoxin
Lanoxin
30
Excreted: Digoxin or Digitoxin
Digoxin
31
Common Brand name of Digitoxin
Reslanoside
32
Scientific name of Foxglove/Purple Foxglove
Digitalis purpurea
33
Scientific name of Grecian Foxglove
Digitalis lanats
34
What type of glycoside is G-strophanthin
Rhamnose Glycoside
34
Toxic component of the Strophanthus plant
G-Strophanthin
35
G-Strophanthin is also known as?
Ouabain
36
Used for preparation of ouabain injection
G-Strophanthus
37
30% of Fixed oil, the bases trigonelline and choline, resin and mucilage
Strophanthus kombe (K-Strophanthus)
38
4-8% of Ouabain
Strophanthus gratus (G-Strophanthus)
39
Toxic moiety that should not be a constituent of Squill
Red Moiety
39
What is Red Moiety used for
Used more in rodenticides
40
Which among the 3 consituents of Black Hellebore have a digitalis-like action
Helleborein, Hellebrin
41
3 Constituents of Black Hellbore
1. Helleborin 2. Helleborein 3. Hellebrin
42
Bufadienolide analogue of Strophanthin
Hellebrigenin
43
What is 20 times more powerful than Helleborein
Hellebrin
43
Hellebores: White and Green are? Black is?
White and Green are cardiac depressant Black is cardiac stimulant
44
Bufadienolide or Cardenolide? Squill
Bufadienolide
44
Bufadienolide or Cardenolide? Red Squill
Bufadienolide
44
Bufadienolide or Cardenolide? Indian Squill/Urginea
Bufadienolide
44
Bufadienolide or Cardenolide? Black Hellebore Rhizome
Bufadienolide
45
Bufadienolide or Cardenolide? Digitalis leaf
Cardenolide
45
Bufadienolide or Cardenolide? Strophanthus
Cardenolide
45
Bufadienolide or Cardenolide? Oleander
Cardenolide
45
Bufadienolide or Cardenolide? Convallaria
Cardenolide
45
Family of Convallaria majalis
Liliaceae
45
What properties do Convallaria have
Cardioactive properties, which are similar to those of digitalis but much less cumulative
45
Where are Convallaria collected from?
Aerial parts, rhizomes, and roots
46
What does Convallatoxin give after getting hydrolysed
Strophanthin and Rhamnose
46
Contains minor cardenolides, 40 glycosides with nine different aglycone
Convallaria majalis
46
A glycoside of the Convallaria seeds
Convalloside
47
When Convalloside is acted on what does it yield
Convallatoxin and dglucose
48
What is extracted from leaves of Convalloside
flavonoids
48
From the hydrolysis of glycose, cymarose and periplogenin
Periplocin
49
What is extracted from roots of Convalloside
Saponin, 3 Sugar chains at C1,C2,C7
49
Color of anthraquinone derivatives?
Orange
49
From the hydrolysis strophanthidin and digtoxose
Erysimin
49
What is appropriate solvent of Chrysarobin
Hot Benzene
49
Is Anthraquinone a sugar or non sugar?
Nonsugar (Algycone)
50
ID Test of Anthraquinone
Bontrager Test
50
Cascarosides A and B?
Barbaloin
50
What is the use of Anthraquinone Glycosides?
Cathartics, EXCEPT Chrysarobin
51
Cascarosides C and D?
Chrysaloin
52
Drug name of Frangula Buckthorn Black
Movicol Component: Frangula and (Sterculia) Karaya
52
Can be a treatment for burns
Aloe
53
At what % can Aloe be a treatment
2%
54
What is the active constiuent of Aloe
Barbaloin
55
Can cause skin change or Keratolytic
Chrysarobin
56
Chrysarobin is toxic in nature, so what was the semisynthetic that replaced Chrysarobin?
Anthralin

2nd Year - 1st Sem (26 decks)

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