(Finals) MicroBio Lec Quiz 1 Flashcards
Scientific study of disease
Pathology
Pathology is concerned with?
- Etiology
- Pathogenesis
- Structural and Functional Changes
Invasion or Colonization of the body by pathogenic microorganisms
Infection
Presence of a particular type of microorganism in part of body where it is not normally found
Infection
When an infection results in any change from a state of health
Disease
Abnormal state in which part or all of the body is incapable of performing its normal function
Disease
4 organisms that begin to establish themselves in an individual before birth
Enterobacteriaceae
Propionibacterium
Lactobacillus
E. coli
Microorganisms that establish more or less permanent residence (colonize) but do not produce disease under normal conditions
Normal Flora/Normal Microbiota
Several days, weeks, or months then disappear
Transient Microbiota
The factors that determine the distribution and composition of normal microbiota
Nutrients
Physical and Chemical Properties
Host’s Defenses
Mechanical Factors
Normal flora preventing the overgrowth of harmful
microorganisms
MICROBIAL ANTAGONISM/ COMPETITIVE EXCLUSION
Competing for nutrients, producing substances harmful to invading microbes, and affecting conditions such as pH and available oxygen
MICROBIAL ANTAGONISM/ COMPETITIVE EXCLUSION
Relationship between 2 organisms in which at least 1 organism is dependent on the other
SYMBIOSIS
1 organism benefits while the other is unaffected
COMMENSALISM
Example microorganism of Commensalism
Staphylococcus epidermidis (Skin)
Both organisms benefit
Mutualism
Example of microorganism of Mutualism
E. Coli (Large Intestine)
1 Organism benefits by deriving nutrients at the expense of the other
Parasitism
Example of Parasitism
Disease-causing bacteria
Microorganisms that don’t cause disease in their normal habitat in a normal healthy person but may do so in a different environment
OPPORTUNISTIC MICROORGANISMS
True or False:
If the host is already weakened or compromised by infection, microbes that are usually harmless cannot cause disease
False
Microbes that are harmless CAN CAUSE disease if the host is weakened or compromised by infection
What are stated in Koch’s Postulation
The same pathogen must be present in every case of the disease
The pathogen must be isolated from the diseased host and grown in pure culture
The pathogen from the pure culture must cause the disease when it’s inoculated into a healthy, susceptible lab animal
The pathogen must be isolated from the inoculated animal and must be shown to be the original organism
Exemptions to Koch’s Postulates
- Microorganisms with unique culture requirements
- Requires some modifications of Koch’s Postulates and the use of alternative methods of culturing and detecting certain microorganisms
- Certain pathogens exhibits certain signs and symptoms