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2nd Year - 1st Sem > (Midterms) DDS Lec Quiz 1 > Flashcards

(Midterms) DDS Lec Quiz 1 Flashcards

1
Q

solid dosage forms usually prepared with the aid of suitable pharmaceutical excipients.

A

Tablet

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2
Q

Tablets are prepared primarily by _______ with a limited number prepared by __________

A

Compression; Molding

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3
Q

Manufactured with tablet machines capable of exerting great pressure

A

Compressed Tablets

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4
Q

Shapes of compressed tablets are determined by the use of what?

A

Shaped punches and dies

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5
Q

Prepared on a large scale by tablet machinery or on a small scale by manually forcing dampened powder material into a mol

A

Molded Tablets

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6
Q

add the necessary bulk to a formulation to prepare tablets

A

Diluents/Fillers

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7
Q

Promote adhesion of the particles of the formulation

A

Binders/Adhesives

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8
Q

Promote breakup of the tablets after administration

A

Disintegrants

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9
Q

There are colorants and flavorants in the tablet

A

Miscellaneous adjunts

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10
Q

Antiadherents, glidants, or lubricants do the following:

A
  1. enhance the flow of the material into the tablet dies
  2. minimize wear of the punches and dies
  3. prevent fill material from sticking to the punches and dies
  4. produce tablets with a sheen
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11
Q

Prepared by subjecting the fill material to more than a single compression

A

Multiple Compressed Tablets

can be:
- multiple-layer tablet
- tablet within a tablet

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12
Q

may be coated with a colored or an uncolored sugar layer.

A

Sugarcoated Tablets

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13
Q

True or False:

Sugarcoated tablets are water soluble

A

True

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14
Q

How much percentage does sugarcoating add to the weight and bulk of the uncoated tablet

A

50%

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15
Q

Tablets that allow the patients to swallow smaller portions of it in divided dosage

A

Scored/Grooved Tablets

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16
Q

True or False:

I can break tablets that are not scored

A

False

Tablets that are not scored are not intended to be broken or cut as this could alter the tablet’s physical integrity

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17
Q

Compressed tablets coated with a thing layer of a polymer

A

Film-Coated Tablets

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17
Q

Prepared on a large scale by tablet machinery

A

Molded tablet

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18
Q

Steps in sugarcoating tablets

A
  1. Waterproofing and sealing
  2. Sub-coating
  3. Smoothing and final rounding
  4. Finishing and coloring
  5. Polishing
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19
Q

Advantages of Film-coated tablets over sugarcoated

A
  • More durable
  • Less bulky
  • Less time-consuming to apply
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20
Q

Film-coating solutions may be:

A

Aqueous or nonaqueous

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20
Q

Capable of producing smooth, thin films reproducible under conventional coating conditions and applicable to a variety of tablet shapes

A

Film former

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21
Q

Make the appearance of the coated tablets handsome and distinctive

A

Opaquants and colorants

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21
Q

Providing water solubility or permeability to the film to ensure penetration by body fluids and therapeutic availability of the drug

A

Alloying substance

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22
Produce flexibility and elasticity of the coating and thus provide durability
Plasticizer
22
Enhance spreadability of the film during application
Surfactant
23
Provide luster to the tablets without a separate polishing operation.
Glossant
24
Enhance the acceptability of the tablet by the patient
Sweeteners, flavors, and aromas
25
Percentage of Film-forming polymer (Aqueous)
7-18%
25
Allow the spread of the other components over the tablets while allowing rapid evaporation to permit an effective yet speedy operation
Volatile solvent
26
Percentage of Plasticizer (Aqueous)
0.5-2.0%
27
Percentage of Colorant and opacifier
2.5-8%
28
Percentage of vehicle
Water: To make 100%
28
Recent innovation tablet
Gelatin-coated tablet
29
A capsule-shaped compressed tablet that allows the coated product to be about 1/3 smaller than a capsule filled with an equivalent amount of powder.
Gelatin-coated Tablets
30
Tablets with delated release features
Enteric-coated Tablets
31
Tablets designed to pass unchanged through the stomach to the intestines where the tablets disintegrate
Enteric-coated Tablets
32
Flat, oval tablets intended to be dissolved in the buccal pouch
Buccal Tablets
33
Flat, oval tablets intended to be dissolved beneath the tongue
Sublingual tablets
34
What absorbs sublingual and buccal tablets
Oral Mucosa
35
Tablets that have a smooth, rapid disintegration when chewed or allowed to dissolve in the mouth
Chewable Tablets
36
Tablets that are useful for administration of large tablets to children and adults who have difficulty swallowing solid dosage forms
Chewable Tablets (Rapidly Disintegrating Tablets - also designed for children and elderly who has difficulty swallowing tablets, they liquefy on the tongue and patients swallows the liquid)
37
Chewable does not contain these, in which why we need to chew these tablets
Disintegrants Chewables have no disintegrants
38
The excipient in chewable tablets
Mannitol
39
Excipient in sugar-free chewable tablets
Xylitol
40
Prepared by compressing granular effervescent salts that release gas when in contact with water
Effervescent Tablets
41
Small, usually cylindrical, molded, or compressed tablets containing small amounts of usually potent drugs.
Tablet triturates
42
Tablets that are no longer in the US, were originally used by physicians in extemporaneous preparation of parenteral solutions
Hypodermic Tablets
43
Tablets that are designed to disintegrate and release their medication with no special rate-controlling features
Immediate-Release Tablts
44
Tablets that are characterized by disintegrating or dissolve in the mouth within 1 minute, some even within 10 seconds
Rapidly Disintegrating or Dissolving Tablets
45
Tablets designed to release their medication in a predetermined manner over an extended perior
Extended-release tablets
45
Extended-release tablets are also known as what
Controlled-release tablets
46
Uncoated, bullet-shaped ovoid tablets inserted into the female private part for local effects
Vaginal Tablets
47
Vaginal tablets aka?
Vaginal inserts
48
Vaginal tablets contain these for the treatment of nonspecific vaginitis
Antibacterials
49
What is the bacteria that causes nonspecific vaginitis
Haemophilus vaginalis
50
Vaginal tablets contain these for the treatment of vulvovaginitis candidiasis
Antifungals
51
What is the bacteria that causes vulvovaginitis candidiasis
Candida albicans
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2nd Year - 1st Sem (26 decks)

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