(Midterms) DDS Lec Quiz 1 Flashcards

1
Q

solid dosage forms usually prepared with the aid of suitable pharmaceutical excipients.

A

Tablet

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2
Q

Tablets are prepared primarily by _______ with a limited number prepared by __________

A

Compression; Molding

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3
Q

Manufactured with tablet machines capable of exerting great pressure

A

Compressed Tablets

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4
Q

Shapes of compressed tablets are determined by the use of what?

A

Shaped punches and dies

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5
Q

Prepared on a large scale by tablet machinery or on a small scale by manually forcing dampened powder material into a mol

A

Molded Tablets

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6
Q

add the necessary bulk to a formulation to prepare tablets

A

Diluents/Fillers

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7
Q

Promote adhesion of the particles of the formulation

A

Binders/Adhesives

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8
Q

Promote breakup of the tablets after administration

A

Disintegrants

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9
Q

There are colorants and flavorants in the tablet

A

Miscellaneous adjunts

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10
Q

Antiadherents, glidants, or lubricants do the following:

A
  1. enhance the flow of the material into the tablet dies
  2. minimize wear of the punches and dies
  3. prevent fill material from sticking to the punches and dies
  4. produce tablets with a sheen
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11
Q

Prepared by subjecting the fill material to more than a single compression

A

Multiple Compressed Tablets

can be:
- multiple-layer tablet
- tablet within a tablet

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12
Q

may be coated with a colored or an uncolored sugar layer.

A

Sugarcoated Tablets

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13
Q

True or False:

Sugarcoated tablets are water soluble

A

True

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14
Q

How much percentage does sugarcoating add to the weight and bulk of the uncoated tablet

A

50%

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15
Q

Tablets that allow the patients to swallow smaller portions of it in divided dosage

A

Scored/Grooved Tablets

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16
Q

True or False:

I can break tablets that are not scored

A

False

Tablets that are not scored are not intended to be broken or cut as this could alter the tablet’s physical integrity

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17
Q

Compressed tablets coated with a thing layer of a polymer

A

Film-Coated Tablets

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17
Q

Prepared on a large scale by tablet machinery

A

Molded tablet

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18
Q

Steps in sugarcoating tablets

A
  1. Waterproofing and sealing
  2. Sub-coating
  3. Smoothing and final rounding
  4. Finishing and coloring
  5. Polishing
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19
Q

Advantages of Film-coated tablets over sugarcoated

A
  • More durable
  • Less bulky
  • Less time-consuming to apply
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20
Q

Film-coating solutions may be:

A

Aqueous or nonaqueous

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20
Q

Capable of producing smooth, thin films reproducible under conventional coating conditions and applicable to a variety of tablet shapes

A

Film former

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21
Q

Make the appearance of the coated tablets handsome and distinctive

A

Opaquants and colorants

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21
Q

Providing water solubility or permeability to the film to ensure penetration by body fluids and therapeutic availability of the drug

A

Alloying substance

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22
Q

Produce flexibility and elasticity of the coating and thus provide durability

A

Plasticizer

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22
Q

Enhance spreadability of the film during application

A

Surfactant

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23
Q

Provide luster to the tablets without a separate polishing operation.

A

Glossant

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24
Q

Enhance the acceptability of the tablet by the patient

A

Sweeteners, flavors, and aromas

25
Q

Percentage of Film-forming polymer (Aqueous)

A

7-18%

25
Q

Allow the spread of the other components over the tablets while allowing rapid evaporation to permit an effective yet speedy operation

A

Volatile solvent

26
Q

Percentage of Plasticizer (Aqueous)

A

0.5-2.0%

27
Q

Percentage of Colorant and opacifier

A

2.5-8%

28
Q

Percentage of vehicle

A

Water: To make 100%

28
Q

Recent innovation tablet

A

Gelatin-coated tablet

29
Q

A capsule-shaped compressed tablet that allows the coated product to be about 1/3 smaller than a capsule filled with an equivalent amount of powder.

A

Gelatin-coated Tablets

30
Q

Tablets with delated release features

A

Enteric-coated Tablets

31
Q

Tablets designed to pass unchanged through the stomach to the intestines where the tablets disintegrate

A

Enteric-coated Tablets

32
Q

Flat, oval tablets intended to be dissolved in the buccal pouch

A

Buccal Tablets

33
Q

Flat, oval tablets intended to be dissolved beneath the tongue

A

Sublingual tablets

34
Q

What absorbs sublingual and buccal tablets

A

Oral Mucosa

35
Q

Tablets that have a smooth, rapid disintegration when chewed or allowed to dissolve in the mouth

A

Chewable Tablets

36
Q

Tablets that are useful for administration of large tablets to children and adults who have difficulty swallowing solid dosage forms

A

Chewable Tablets

(Rapidly Disintegrating Tablets - also designed for children and elderly who has difficulty swallowing tablets, they liquefy on the tongue and patients swallows the liquid)

37
Q

Chewable does not contain these, in which why we need to chew these tablets

A

Disintegrants

Chewables have no disintegrants

38
Q

The excipient in chewable tablets

A

Mannitol

39
Q

Excipient in sugar-free chewable tablets

A

Xylitol

40
Q

Prepared by compressing granular effervescent salts that release gas when in contact with water

A

Effervescent Tablets

41
Q

Small, usually cylindrical, molded, or compressed tablets containing small amounts of usually potent drugs.

A

Tablet triturates

42
Q

Tablets that are no longer in the US, were originally used by physicians in extemporaneous preparation of parenteral solutions

A

Hypodermic Tablets

43
Q

Tablets that are designed to disintegrate and release their medication with no special rate-controlling features

A

Immediate-Release Tablts

44
Q

Tablets that are characterized by disintegrating or dissolve in the mouth within 1 minute, some even within 10 seconds

A

Rapidly Disintegrating or Dissolving Tablets

45
Q

Tablets designed to release their medication in a predetermined manner over an extended perior

A

Extended-release tablets

45
Q

Extended-release tablets are also known as what

A

Controlled-release tablets

46
Q

Uncoated, bullet-shaped ovoid tablets inserted into the female private part for local effects

A

Vaginal Tablets

47
Q

Vaginal tablets aka?

A

Vaginal inserts

48
Q

Vaginal tablets contain these for the treatment of nonspecific vaginitis

A

Antibacterials

49
Q

What is the bacteria that causes nonspecific vaginitis

A

Haemophilus vaginalis

50
Q

Vaginal tablets contain these for the treatment of vulvovaginitis candidiasis

A

Antifungals

51
Q

What is the bacteria that causes vulvovaginitis candidiasis

A

Candida albicans

52
Q
A
53
Q
A
54
Q
A
55
Q
A
56
Q
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57
Q
A
58
Q
A
59
Q
A
60
Q
A
61
Q
A