Micturition Flashcards

1
Q

Why do men’s bladders work at a higher pressure than womens? [1]

A

Male urethra is longer - requires greater pressure to push further

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2
Q

Explain how the micturition reflex works

A

Full bladder: sensory feedback from S2-4) to micturition centre

micturition centre sends signal to brain to ask if socailly acceptable to urinate or not

if yes: able to control sphincter via somatic nature of pudendal nerve AND parasympathetic action of detrusor muscle, contracting the bladder

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3
Q

FYI

A
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4
Q

The bladder spends most of time in [] mode

A

storage mode - only contracts 0.3% of life !

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5
Q

Normal bladder contraction is caused by the release of []

The release of [] causes the stimulation of [] receptors on the [] smooth muscle

A

Normal bladder contraction is caused by the release of Ach

The release of Ach causes the stimulation of muscarininc receptors on the detrusor smooth muscle

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6
Q

What are lower urinary tract symptoms?

  • storage symptoms? [4]
  • voiding symptoms? [5]
  • post-micturition [2]

What is important to recogonise with them?

A

Storage symptoms:
- frequency
- nocturia
- urgency
- urge inconteninence

Voiding symptoms:
* Hesitancy
* Straining
* Poor flow
* Intermittency
* Incomplete emptying

post-micturition:
* dribbling

Most of the time the symptoms present together / not individually to voiding symptoms

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7
Q

What is an overactive bladder? [1]

What do ptx normally present with? [2]

A

inability to postpone voiding - need to urinate

usually present wtih nocturia
may present with incontinence

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8
Q

FYI Diagnosis

A
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9
Q

Most important question to ask with a patient is what? [1]

A

How bad is it? (can they live with symptoms)

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10
Q

Which diagnostic score would use to assess micruition? [2]

What would scores be for mild, moderate and severe? [3]

A

Internation Prostate Symptom Score (IPSS)

Mild: 0-7
Moderate: 8-19
Severe: 20-35

AND

Input / Output Chart = voiding diary to create a frequency / volume chart

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11
Q

How would you investigate micturition problems? [6]

A
  • inspect fresh urine sample
  • urine dipstick
  • FBC, PSA (prostatic specific antigen)
  • Uroflowmetry
  • Ultrasound and CT scans
  • Nuclear imaging (for kidney obstruction)
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12
Q

What does a normal flow-rate recording look like?

A

Fast and short
20 ml/s = unobstructed

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13
Q

How does urinary flow rate change with age? [1]

A

Decreases with age

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14
Q

Most common is to have:

voiding symptoms only
storage symptoms only
post-micturition symptoms only
storage & voiding symptoms
storage & voiding & post-mic symptoms

A

Most common is to have:

voiding symptoms only
storage symptoms only
post-micturition symptoms only
storage & voiding symptoms
storage & voiding & post-mic symptoms

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15
Q

What is an important consideration with regards to treating bladders?

A

When a bladder is obstructed, starts to contract a bit randomly: causes changes in pressure (and symptoms)

Bladder isnt overactive - is just blocked.

If treat overactivity then might not do anything - so need to treat blockages

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16
Q

What are 3 classifications for micturition disorders? [3]

A

anatomical disorders
* obstruction
* incontinence

functional disorders
* stroke / spinal cord injury / neurological disease

Medical disorders
* Cardiac, hepatic and renal failure

17
Q

OR can think of classifications of mic. disorders in which way? [4]

A
18
Q

Describe pathophysiology of benign prostate hyperplasia

A

Prostate undergoes hyperplasia - obstructs urethra

Causes detrusor hyperplasia

19
Q

Name some Conservative management for lifestyle advise? [6]

A

Fluid
Type
Amount
Bladder Drill
Food
Smoking
Urethral Milking
Pads & Convenes

NOT CATHETERS! – last resort, and CISC best type

20
Q

How can you adapt fluid management for patients?

What is aim for ml of urine per day?

How can you measure how much urine making each day?

A

Wee more / less depending on fluid intake

Dehydrated urine causes bladder iritation

Aim for 1500ml - 2000ml urine

Measure using voding diary

21
Q

Effect of caffeine on bladder? [1]

A

Causes release of calcium stores from GA in the bladder wall

Causes contraction more likely

22
Q

What is a big risk factor for bladder cancer? [1]

What foods are risks for bladder irritation? [3]

A

smoking

onions, chilli and spicy food

23
Q

What is urethral milking?

A

Put hands behind testicles and bring forward after urinating to ensure all urine is expelled from U bend in urethra (stops dribbling)

24
Q

Explain drugs used to treat bladder problems [4]

A

alpha blockers(‘stretchers’): stretch prostates open

5-alpha reductase Inhibitors: (‘shrinkers’) shrink prostates

PDE5 inhibitors

Antimuscarinics (for OAB)

Combination

25
Q

FYI

A

Also get surgery for LUTS

26
Q

What is difference between stress and urge urinary incontinence? [2]

A

Stress UI: Leakage on effort or exertion (increased abdominal pressure)

Urge UI: Leakage accompanied by urgency

26
Q

What is difference between stress and urge urinary incontinence? [2]

A

Stress UI: Leakage on effort or exertion (increased abdominal pressure)

Urge UI: Leakage accompanied by urgency

27
Q

Explain how stress incontinence occurs

A

weaking of pelvic floor or urethral sphincter

support is diminished, this causes intra-abdominal pressure to push more urine into urethra

28
Q

Explain how urge incontinence occurs

A

Larger squeezes on bladder muscle occur

overcomes sphincter and urine comes out urethra

29
Q

How do you prioritise treatment options for urge incontinence / overactive bladder? [7]

A
  1. Always treat overactive component first
  2. Next approach conservative measures (fluid intake / caffiene / pads)
  3. Next pelvic floor exercises
  4. Tablets
  5. Botox
  6. Posterior and / or sacral nerve stimulation
  7. surgery
30
Q

Explain 3 drugs used for urge incontinence / OAB [3]

A
31
Q

Where in the body are regions safe if neurogenic damage occurs? [2]

Where is not safe? [1]

A

Safe:
- Lesions above pontine micturition centre
- Lesions below T12

Unsafe:
- Between mic. centre and T12: causes loss of coordination and raises bladder pressure