Microbio - UTI Flashcards
What population is generally classed as uncomplicated UTI?
Non-pregnant women
What population is generally classed as complicated UTI?
Pregnant women, men, and structural abnormality to urinary tract
*Most common overall organism
E. Coli
*Most common organism in young women
Staph. saprophyticus
Most common organism for hospital acquired
Proteus, Klebsiella
Most common organism for haematogenous
Staph aureus
UTI general presentation
Frequency, urgency, dysuria, abdo pain
UTI presentation elderly
non-specific, delirium
Pyelonephritis presentation
systemically unwell, fever + rigors, loin pain
What is urosepsis
Sepsis due to UTI
UTI investigations
- Dipstick
- MC&S
What may you find on urine dipstick for UTI?
Nitrites and leukocytes +
± haematuria
Whether to treat UTI based off urine dip results:
- Nitrite +ve
- Nitrite -ve, leukocyte +ve
- Nitrite -ve, leukocyte-ve
- UTI -> Treat
- ?UTI -> ?treat, culture
- Not UTI
Diagnostic MC&S results for UTI (2)
- >103 CFU/ml E.coli or S. saprophyticus
- >104 CFU/ml other organisms
*What MC&S results mean contamination?
Mixed growth, squamous epithelium/ mixture of staphs and streps
Management for UTI
nitrofurantoin / trimethoprim / phenytoin/ cephalexin / amoxicillin
3d if uncomplicated; 7d if complicated
Management for clinically unwell pyleonephritis
admit, IV co-amox + gentamycin
*Which organism is associated with renal calculi formation?
Proteus mirabilis
*Between nitrites and leukocyte on urine dip, which is more sensitive for UTI and which is more specific?
Leukocyte more sensitive
Nitrite more specific
(Nitrite miight be better overall then?)
