Micro 3 CNS

Question 1

Strep Pneumoniae micro

Answer 1

G+ diplococcus

• Alpha hemolytic (green sheen)
• Optochin sensitive

Question 2

Strep Pneumoniae virulence

Answer 2

• IgA protease

- Antiphagocytic capsular variation -> many different serotypes

Question 3

Strep Pneumoniae Tx

Answer 3

Ceftriaxone

-Vancomycin for resistant strains

Question 4

Strep Pneumoniae otitis media Tx

Answer 4

Amoxicillin-Clavulanate

Question 5

Strep Pneumoniae vaccine

Answer 5

Only against meningitis and bacteremia, not against pneumonia

Question 6

Haemophilus Influenzae micro

Answer 6

G- coccobacilli

-Needs Hemin and NAD to grow

Question 7

Haemophilus influenzae disease

Answer 7

Meningitis

• Epiglottitis
• Septic arthritis

Question 8

Haemophilus influenzae virulence

Answer 8

Antiphagocytic capsule (type B)
-IgA protease

Question 9

Haemophilus influenzae Tx

Answer 9

Ceftriaxone

Question 10

Haemophilus influenzae vaccine

Answer 10

Hib (type B)

-Given at 2 months, very effective

Question 11

Listeria monocytogenes micro

Answer 11

G+ coccobacilli in short chains

• B hemolytic
• Blue/green translucent colonies
• Replicates at 4*C

Question 12

Listeria monocytogenes risk group

Answer 12

Neonates, immunocompromised, pregnancy

Question 13

Listeria monocytogenes disease

Answer 13

Granulomatosis Infantiseptica (in utero)

• Acute febrile gastroenteritis
• Meningoencephalitis

Question 14

Listeria virulence

Answer 14

Listeriolysin O and phospholipases disrupt phagocytic vacuole
-Actin mobilization to penetrate neighboring cells (avoid humor)

Question 15

Listeria Tx

Answer 15

Ampicillin & Gentamycin

Question 16

Cryptococcus neoformans

Answer 16

Spread through pigeon droppings

-Only in immunocompromised

Question 17

Cryptococcus neoformans Tx

Answer 17

Fluconazole and Amphotericin B