Micro 14 HIV Flashcards
1
Q
HIV pneumonia
A
PCP - pneumocystis carinii pneumonia
-Histoplasmosis
2
Q
First antiretroviral drug
A
Zidovudine
3
Q
HIV micro
A
enveloped ssRNA
4
Q
HIV Dx protein
A
gag (group specific antigen)
5
Q
HIV binding protein
A
gp120
6
Q
HIV fusion protein
A
gp41
7
Q
TH1 v TH2 response
A
Cell mediated (CD8) v. Humoral (Plasma, Ab)
8
Q
AIDS tongue infection
A
Hairy leukoplakia (Lytic EBV)
9
Q
AIDS eye infection
A
CMV retinitis
10
Q
AIDS mycobacteria avium infection
A
Lungs, GI, bone (neutropenia)
11
Q
CMV Tx
A
Ganciclovir - neutropenia
Cidofovir - nephrotoxic
12
Q
HIV brain infection
A
Macrophages -> microglial
13
Q
HIV neuropathology
A
Encephalitis with perivascular cuffing and microglial nodules
14
Q
HIV pulmonary pathology
A
LIP - Lymphoid Interstitial Pneumonitis
15
Q
HIV renal pathology
A
HIVAN - HIV Associated Nephropathy
- focal segmental glomerulosclerosis
- interstitial nephritis
- mesangial cell hyperplasia
