Micro 11 Systemic Flashcards
Salmonella typhi micro
G- rods
Capsule
Non lactose-fermenting
Salmonella reservoir
Poultry
Salmonella paratyphi disease
Gastroenteritis
Salmonella typhi disease
Enteric (typhoid) fever
- Rose spots (papular rash on trunk)
- Inflammatory diarrhea/constipation
- Intestinal perforation (Peyer’s patch)
- Bacteremia, Bone infection, fever
- Hepatosplenomegaly
Typhoid Tx
Ceftriaxone
Fluoroquinolone
Typhoid Dx
Blood or bone marrow cultures
-Stool/urine cultures
S. typhi virulence
Phase variation (genetic recombination) produces different H (flagella) antigens
Brucellosis
Malta fever
Brucella reservoir
Milk, cheese (sheep, goats in mediterranean)
Brucella micro
G- coccobacilli
Brucellosis
Acute - undulating fever, drenching sweats
Chronic - Granulomas in lymph, liver, bone (reticuloendothelial system)
Brucella Dx
Serology
Brucella Tx
Doxycycline
Rifampin or Gentamycin
Q fever pathogen
Coxiella burnetii
Coxiella micro
G- coccobacilli, intracellular
-Spores
Coxiella reservoir
Australia animals (inhalation of spores)
Q fever symptoms
Acute - Fever, atypical pneumonia
Chronic - Endocarditis (culture negative)
Coxiella burnetii Dx
Serology
Acute - phase 2
Chronic - phase 1,2
Coxiella Tx
Tetracycline
Ehrlichia micro
G- coccobacilli, intracellular
Ehrlichia reservoir
Ticks
Ehrlichosis
Fever, leukopenia, thrombocytopenia, elevated AST/ALT
Ehrlichosis Dx
Serology
Ehrlichosis Tx
Doxycycline
