Micro 11 Systemic Flashcards

1
Q

Salmonella typhi micro

A

G- rods
Capsule
Non lactose-fermenting

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2
Q

Salmonella reservoir

A

Poultry

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3
Q

Salmonella paratyphi disease

A

Gastroenteritis

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4
Q

Salmonella typhi disease

A

Enteric (typhoid) fever

  • Rose spots (papular rash on trunk)
  • Inflammatory diarrhea/constipation
  • Intestinal perforation (Peyer’s patch)
  • Bacteremia, Bone infection, fever
  • Hepatosplenomegaly
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5
Q

Typhoid Tx

A

Ceftriaxone

Fluoroquinolone

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6
Q

Typhoid Dx

A

Blood or bone marrow cultures

-Stool/urine cultures

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7
Q

S. typhi virulence

A

Phase variation (genetic recombination) produces different H (flagella) antigens

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8
Q

Brucellosis

A

Malta fever

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9
Q

Brucella reservoir

A

Milk, cheese (sheep, goats in mediterranean)

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10
Q

Brucella micro

A

G- coccobacilli

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11
Q

Brucellosis

A

Acute - undulating fever, drenching sweats

Chronic - Granulomas in lymph, liver, bone (reticuloendothelial system)

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12
Q

Brucella Dx

A

Serology

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13
Q

Brucella Tx

A

Doxycycline

Rifampin or Gentamycin

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14
Q

Q fever pathogen

A

Coxiella burnetii

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15
Q

Coxiella micro

A

G- coccobacilli, intracellular

-Spores

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16
Q

Coxiella reservoir

A

Australia animals (inhalation of spores)

17
Q

Q fever symptoms

A

Acute - Fever, atypical pneumonia

Chronic - Endocarditis (culture negative)

18
Q

Coxiella burnetii Dx

A

Serology
Acute - phase 2
Chronic - phase 1,2

19
Q

Coxiella Tx

A

Tetracycline

20
Q

Ehrlichia micro

A

G- coccobacilli, intracellular

21
Q

Ehrlichia reservoir

A

Ticks

22
Q

Ehrlichosis

A

Fever, leukopenia, thrombocytopenia, elevated AST/ALT

23
Q

Ehrlichosis Dx

A

Serology

24
Q

Ehrlichosis Tx

A

Doxycycline

25
Q

Mycobacteria reservoir

A

Soil, people for TB

26
Q

Mycobacteria micro

A

Acid fast (no LPS, outer membrane)

27
Q

Miliary TB

A

Lungs -> lymph/blood -> CNS, liver, bone, lungs

28
Q

TB Tx

A

Isoniazid, rifampin, ethambutol, pyrazinamide

29
Q

Vertebral osteomyelitis

A

Brucellosis