Micro 18 - MIcro By Systems Part 2 Flashcards
What one thing do we see in primary syphilis? What 1 thing in secondary? What three things in tertiary?
Primary: Painless chancre, Secondary: Condylomata lata, More systemic symptoms. Tertiary: Gumman, Tabis dorsalis, aortitis.
What are the features of early manifestations (first 5 weeks of life) of congenital symphilis?
Hepatosplenomegaly, elevated (LFTs), Hemolytic anemia, jaundice, Rash followed by desquamation of hands and feet, Snuffles (blood-tinged nasal secretions), Radiographic changes at birth: Metaphyseal dystrophy and periostitis).
What are the features of late manifestations (if left untreated in the first three months of life) of congenital symphilis?
Hutchinson teeth (notching or blunting of the upper incisors), Saddle nose deformity, Frontal bossing, Saber shins.
What does HSV-2 cause?
Painful ulcers in the groin area.
What does HSV-1 cause?
Cold sores.
What does Chlamydia cause?
Urethritis, more commonly asymptomatic, salpingitis, infertility.
What are the symptoms of Lymphogranuloma venereum caused by the L1-L3 subtypes of Chlamydia trachomatis?
Genital ulcers, rectal strictures, can be mistaken for IBD.
What are the symptoms of Condylomata acuminata? Which type of HPV causes it?
Genital warts, Koilocyte (squamous cells with perinuclear cytoplasmic clearing, fried egg appearance). Caused by HPV-6, HPV-11.
How is the vaginal pH on Trichomonas infection?
The pH is high.
What are the two organisms that cause Pelvic inflammatory disease (PID)?
Chlamydia trachomatis, Neisseria gonorrhoeae.
What are the symptoms of Pelvic inflammatory disease (PID)?
Cervical motion tenderness, Chandelier sign, Purulent cervical discharge.
What is the progression of Pelvic inflammatory disease (PID) if left unchecked?
Cervicitis/urethritis, endometritis, Salpingitis, Tubo-ovarian abscess, peritonitis, and lastly Fitz-Hugh-Curtis syndrome (Infection of liver capsule).
What are two nosocomial disease in newborn nursery?
CMV, RSV.
What bacteria are the most common cause urinary catheterization?
E.coli, Proteus mirabilis, Pseudomonas, MRSA.
What bacteria is related to Respiratory therapy equipment?
Pseudomonas.
What pathogen is related to Renal dialysis or needle sticks?
Hepatitis B virus.
What pathogen is related to hyperalimentation (parenteral nutrition)?
Candida albicans.
What pathogen is related to Burns?
Pseudomonas.
What pathogen is related to water source?
Legionellae.
What are the results of a TORCHeS infection?
They are infection that causes a congenital malformation, hepatosplenomegaly, jaundice, thrombocytopenia, growth retardation. Mild symptoms on the mother.
What are the three symptoms of toxoplasmosis?
Transmitted by cat feces, causes chorioretinitis, hydrocephalus, intracranial calcifications.
What are three symptoms of Congenital rubella?
PDA, cataracts, deafness. Sometimes the “Blueberry muffin rash” caused by thromobocytopenia.
What is the most common of the TORCHeS infection?
CMV.
What are the symptoms of congenital CMV infection?
Mostly asymptomatic by can cause unilateral hearing loss, seizures, chorioretinitis, hydrocephalus, and intracranial calcifications.
How do we prevent vertical transmission of HIV?
Zidovudine monotherapy, HAART, C-section.
What can HSV cause in newborns?
Temporal lobe encephalitis and vesicular lesions.
What can Parvovirus B19 cause congenitally?
Hydrops fetalis in utero, causing generalized fetal edema.
What are the TORCHeS infection?
Toxoplasma, Other (parvovirus B19), Rubella, CMV, HSV/HIV, Syphilis.
Which STD has clue cells?
Bacterial vaginosis.
Which STD has painless genital ulcers?
Chancre (syphilis).
Which STD has flagellated cells?
Trichomonas.
Which STD causes Strawberry cervix?
Trichomonas.
RFF: Most common reportable STD.
Chlamydia.
RFF: Non-painful, indurated, ulcerated, genital lesion.
Primary syphilis.
RFF: Painful, indurated, ulcerated genital lesion, with exudate.
Chancroid.
RFF: Stippled vaginal epithelial cells on a wet prep of vaginal discharge?
Clue cells in bacterial vaginosis.
RFF: Common treatment for syphilis.
Penicillin.
RFF: Common treatment for Trichomonas.
Metronidazole.
RFF: Common treatment for Chlamydia.
Doxycline or azithromycin.
RFF: Common treatment for gonorrhea?
Ceftriaxone.
Which organisms cause Painless Genital Ulcers?
[Some Girls Love Licorice]
Syphilis, Granuloma inguinale, Lymphogranuloma venereum, painLEss.
Which organism cause Painful Genital ulcers?
[Fellows Hate Candy]
painFul, Herpes Simplex, Chancroid.
What three things can gonorrhea cause?
Urethritis, PID (women), Prostatitis and epididymitis (men).
