Micro 18 - MIcro By Systems Part 2 Flashcards

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1
Q

What one thing do we see in primary syphilis? What 1 thing in secondary? What three things in tertiary?

A

Primary: Painless chancre, Secondary: Condylomata lata, More systemic symptoms. Tertiary: Gumman, Tabis dorsalis, aortitis.

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2
Q

What are the features of early manifestations (first 5 weeks of life) of congenital symphilis?

A

Hepatosplenomegaly, elevated (LFTs), Hemolytic anemia, jaundice, Rash followed by desquamation of hands and feet, Snuffles (blood-tinged nasal secretions), Radiographic changes at birth: Metaphyseal dystrophy and periostitis).

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3
Q

What are the features of late manifestations (if left untreated in the first three months of life) of congenital symphilis?

A

Hutchinson teeth (notching or blunting of the upper incisors), Saddle nose deformity, Frontal bossing, Saber shins.

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4
Q

What does HSV-2 cause?

A

Painful ulcers in the groin area.

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5
Q

What does HSV-1 cause?

A

Cold sores.

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6
Q

What does Chlamydia cause?

A

Urethritis, more commonly asymptomatic, salpingitis, infertility.

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7
Q

What are the symptoms of Lymphogranuloma venereum caused by the L1-L3 subtypes of Chlamydia trachomatis?

A

Genital ulcers, rectal strictures, can be mistaken for IBD.

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8
Q

What are the symptoms of Condylomata acuminata? Which type of HPV causes it?

A

Genital warts, Koilocyte (squamous cells with perinuclear cytoplasmic clearing, fried egg appearance). Caused by HPV-6, HPV-11.

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9
Q

How is the vaginal pH on Trichomonas infection?

A

The pH is high.

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10
Q

What are the two organisms that cause Pelvic inflammatory disease (PID)?

A

Chlamydia trachomatis, Neisseria gonorrhoeae.

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11
Q

What are the symptoms of Pelvic inflammatory disease (PID)?

A

Cervical motion tenderness, Chandelier sign, Purulent cervical discharge.

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12
Q

What is the progression of Pelvic inflammatory disease (PID) if left unchecked?

A

Cervicitis/urethritis, endometritis, Salpingitis, Tubo-ovarian abscess, peritonitis, and lastly Fitz-Hugh-Curtis syndrome (Infection of liver capsule).

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13
Q

What are two nosocomial disease in newborn nursery?

A

CMV, RSV.

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14
Q

What bacteria are the most common cause urinary catheterization?

A

E.coli, Proteus mirabilis, Pseudomonas, MRSA.

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15
Q

What bacteria is related to Respiratory therapy equipment?

A

Pseudomonas.

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16
Q

What pathogen is related to Renal dialysis or needle sticks?

A

Hepatitis B virus.

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17
Q

What pathogen is related to hyperalimentation (parenteral nutrition)?

A

Candida albicans.

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18
Q

What pathogen is related to Burns?

A

Pseudomonas.

19
Q

What pathogen is related to water source?

A

Legionellae.

20
Q

What are the results of a TORCHeS infection?

A

They are infection that causes a congenital malformation, hepatosplenomegaly, jaundice, thrombocytopenia, growth retardation. Mild symptoms on the mother.

21
Q

What are the three symptoms of toxoplasmosis?

A

Transmitted by cat feces, causes chorioretinitis, hydrocephalus, intracranial calcifications.

22
Q

What are three symptoms of Congenital rubella?

A

PDA, cataracts, deafness. Sometimes the “Blueberry muffin rash” caused by thromobocytopenia.

23
Q

What is the most common of the TORCHeS infection?

A

CMV.

24
Q

What are the symptoms of congenital CMV infection?

A

Mostly asymptomatic by can cause unilateral hearing loss, seizures, chorioretinitis, hydrocephalus, and intracranial calcifications.

25
Q

How do we prevent vertical transmission of HIV?

A

Zidovudine monotherapy, HAART, C-section.

26
Q

What can HSV cause in newborns?

A

Temporal lobe encephalitis and vesicular lesions.

27
Q

What can Parvovirus B19 cause congenitally?

A

Hydrops fetalis in utero, causing generalized fetal edema.

28
Q

What are the TORCHeS infection?

A

Toxoplasma, Other (parvovirus B19), Rubella, CMV, HSV/HIV, Syphilis.

29
Q

Which STD has clue cells?

A

Bacterial vaginosis.

30
Q

Which STD has painless genital ulcers?

A

Chancre (syphilis).

31
Q

Which STD has flagellated cells?

A

Trichomonas.

32
Q

Which STD causes Strawberry cervix?

A

Trichomonas.

33
Q

RFF: Most common reportable STD.

A

Chlamydia.

34
Q

RFF: Non-painful, indurated, ulcerated, genital lesion.

A

Primary syphilis.

35
Q

RFF: Painful, indurated, ulcerated genital lesion, with exudate.

A

Chancroid.

36
Q

RFF: Stippled vaginal epithelial cells on a wet prep of vaginal discharge?

A

Clue cells in bacterial vaginosis.

37
Q

RFF: Common treatment for syphilis.

A

Penicillin.

38
Q

RFF: Common treatment for Trichomonas.

A

Metronidazole.

39
Q

RFF: Common treatment for Chlamydia.

A

Doxycline or azithromycin.

40
Q

RFF: Common treatment for gonorrhea?

A

Ceftriaxone.

41
Q

Which organisms cause Painless Genital Ulcers?

A

[Some Girls Love Licorice]

Syphilis, Granuloma inguinale, Lymphogranuloma venereum, painLEss.

42
Q

Which organism cause Painful Genital ulcers?

A

[Fellows Hate Candy]

painFul, Herpes Simplex, Chancroid.

43
Q

What three things can gonorrhea cause?

A

Urethritis, PID (women), Prostatitis and epididymitis (men).