Metabolic Diseases Flashcards
give example of a qualitative and quantitative bone defect
qualitative: osteomalacia
quantitative: osteoporosis
what is the pathology of osteomalacia
softer bones due to decreased osteoid mineralisation
risk factors for osteomalacia
vit d deficiency, phosphorus deficiency, calcium deficiency,
alcohol, CKD, refeeding synd
what is seen on examination in osteomalacia
small bone deformities, bow leg, square head, pigeon chest
presentation of hypocalcaemia
cramps, paraesthesia, fatigue, seizure, brittle nail
symptoms of osteomalacia
bone pain, pathological fractures, hypocalcaemia symptoms
investigations of osteomalacia
xr,
what is seen on x-ray in osteomalacia
pseudofractures; Looser’s zones
management of osteomalacia
vit D, Ca & phosphate supplements
what is rickets
osteomalacia in children
risk factors for osteoporosis
CCS, malnutrition, CKD, cancer, Cushing’s, hyper/hyperparathyroidism,
pathology of osteoporosis
bone mineral density < 2.5
investigations for osteoporosis
DEXA scan, normal serum Ca & phos
what is type 1 osteoporosis
post-menopause
what is type 2 osteoporosis
old age related