Mental health Flashcards
Condition and Presentation
Anorexia nervosa
serious mental health disorder characterized by self-imposed starvation and a relentless pursuit of extreme thinness.
Subtypes of anorexia
*. Restrictive Subtype: Characterized by minimal food intake and excessive exercise.
- Bulimic Subtype: Involves episodic binge eating followed by behaviors like laxative use or induced vomiting.
ICD-11 Criteria AN:
- Significantly Low Body Weight
- Fear of Gaining Weight
- Distorted Body Image
- Restrictive Eating
DMS-5 criteria anorexia
- Restriction of Energy Intake
- Intense Fear of Gaining Weight
- Body Image Disturbance
Anorexia nervosa pattern patient
- more common in females
- more common in dev countries
- co-occurs with other psychiatric disorders, such as depression and anxiety
Signs and symptoms of anorexia
Hypotension
Bradycardia
Enlarged salivary glands
Lanugo hair (fine hair covering the skin)
Amenorrhoea
BMI- AN vs Bulemia
- bulemia may have normal BMI
AN blood investigations q
- Deranged electrolytes - typically low calcium, magnesium, phosphate and potassium
- Low sex hormone levels (FSH, LH, oestrogen and testosterone)
- Leukopenia
- Raised growth hormone and cortisol levels (stress hormones)
- Hypercholesterolaemia
- Metabolic alkalosis, either due to vomiting or use of diuretics
Managment of AN
- CBT
- MANTRA
- SSRI
When to admit patients for ano
USS test (sit-up, squat, and stand). Admission is also indicated if proximal muscle weakness suggests weak respiratory muscles.
If patients are very unwell the MARSIPAN checklist should be used to guide management.
Refeeding syndrome
A potentially fatal disorder that occurs when nutritional intake is resumed too rapidly after a period of low caloric intake
Symptoms of refeed syndrome
oedema, confusion and tachycardia
Electrolytes in refeed syndrome
Rapidly increasing insulin levels lead to shifts of potassium, magnesium and phosphate from extracellular to intracellular spaces‚ these need to be replenished
Managment of refeed syndrome
- high-dose vitamins (eg. Pabrinex) before feeding commences
- Monitoring with daily bloods and replenishing electrolytes early
- Building caloric intake gradually with the help of a dietitian‚ NICE recommends that refeeding is started at no more than 50% of calorie requirement
cardiac symptoms assoicated with cardiac arrhythmias
Bradycardia and prolonged QTc are often seen
Negative prognostic factors for ano
- Presentation after the age of 20 years‚ difficult to reverse fixed beliefs
- BMI <16 kg/m2
- Marked anxiety when eating in front of others, which indicates issues with socialisation
- Binging/vomiting responds less well to CBT than starvation
Cautions of SSRI
- Avoid in mania
- Should be used with caution in children and adolescents
- Sertraline is best for patients with ischaemic heart disease
SSRI side effects
- GI upset
- Anxiety and agitation
- QT interval prolongation (especially associated with citalopram)
- Sexual dysfunction
- Hyponatraemia
- Gastric Ulcer
Seretonin syndrome triad
- mental status changes
- autonomic hyperactivity
- neuromuscular abnormalities
Managment of Seretonin syndrome
discontinuation of the offending drug and supportive care.
SNRIs side effects
- Nausea
- Insomnia
- Increased heart rate
- Agitation
NaSSAs side effects
Sedation
Increased appetite
Weight gain
Constipation/diarrhoea
TCA cautions
- Contraindicated in those with previous heart disease
- Can exacerbate schizophrenia
- May exacerbate long QT syndrome
- Use with caution in pregnancy and breastfeeding
- May alter blood sugar in T1 and T2 diabetes mellitus
- May precipitate urinary retention, so avoid in men with enlarged prostates
- Uses the Cytochrome P450 metabolic pathway, so avoid in those on other CP450 medications or those with liver damage
TCA side effects
Urinary retention
Drowsiness
Blurred vision
Constipation
Dry mouth