meningitis Flashcards
what is meningitis
inflammation of the meninges
what are the causative agents of meningitis
haemophilus influenza type B
neisseria meningitidis
streptococcus pneumoniae
MOT of meningitis
droplet
contact—-soiled secretions
incubation period of meningitis
2-10 days
diagnostic test for meningitis
lumbar puncture/ tap
spinal puncture/tap
quickenstedts test
s/sx of meningitis
nuchal rigidity
kernig’s sign
brudzinki’s sign
what is nuchal rigidity
inability to flex the neck forward
what is kernig’s sign
pt complains pain upon extension or straightening the KNEE/legs
What is brudzinki’s sign
flexion of the neck causes flexion of the knee
normal color of CSF
colorless, clear
normal amount of CSF
100-150ml (normal production 500ml)
normal glucose in CSF
50-80mg/dl (always decrease in meningitis)
normal protein in csf
20-50 mg/dl (always increase in any infection of the brain)
normal ICP in newborn
2-5mmHg
normal ICP in children
8-10 mmHg
normal ICP in adults
8-15 mmHg
signs of increase ICP
Cushing’s Triad (increase BP, decrease RR, PR)
anisocoria
diplopia
doll’s eye
high fever/chills
N/V
Photosensitivity
Wide pulse pressure
Restlessness
Convulsions/seizures
what is anisocoria
dilated pupils d/t compression of CN3 (occulomotor)
diplopia
this is d/t compression of CN6 (abducens) (longest CN therefore prone to compression)
initial sign of increase ICP
restlessness
normal ICP
75-180mmH2O or 0-15 mmHg
how many minutes do CEREBRAL CORTEXT tolerate HYPOXIA
4-6 mins (irreversible brain damage)
what do cerebral context tolerate?
HYPOXIA
what do MEDULLA OBLONGATA tolerates?
HYPOXIA
how many minutes do MEDULLA OBLONGATA tolerates hypoxia?
10-12 mins (beyond could result to irreversible brain damage)
Pharmacological management for meningitis
ANTIBIOTICS (penG)
OSMOTIC DIURETICS (mannitol)
CORTICOSTEROIDS (dexamethasone)
ANTICONVULSANT
PAIN RELIEVERS (codein) (may headache siya)
ANTACIDS (aluminum or magnesium based)
PPI (zantac/ranitidine)