malaria Flashcards

1
Q

what is malaria

A

caused by female anopheles mosquito

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2
Q

causative agents of malaria

A

PARASITES!!!

  • plasmodium falciparum (most malignant/drug resistance)
  • plasmodium malariae
  • plasmodium vivax
  • plasmodium ovale
  • plasmodium knowleSI
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3
Q

where is the target organ of these causative agents of malaria?

A

liver —- wherein they matures and reproduce

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4
Q

characteristics of female anopheles mosquito

A

night biting ( 9pm-3am)
high flying
free flowing water
rural areas

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5
Q

what is malarial cachexia

A

a general state of weakness that occurs as a result of a long-term chronic malarial infection

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6
Q

malarial cachexia is characterised by

A

jaundice
anemia
splenomegaly
hepatomegaly
emaciation

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7
Q

happens on the 3rd day d/t rupture of erythrocytes

A

malarial cachexia

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8
Q

MOT of malaria

A

vector borne/ bite of female anopheles mosquito

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9
Q

incubation period of malaria

A

10-12 days

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10
Q

s/sx of malaria

cold stage

A

shivering
chills
chatter teeth

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11
Q

s/sx of malaria

hot stage

A

fever 40C or 104F
reddened eyes and skin
warm to touch

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12
Q

s/sx of malaria

wet stage

A

diaphoresis —- prone to dehydration

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13
Q

the s/sx of malaria happens??

A
  • every 2 days if VIVAX , OVALE
  • every 3 days if FALCIPARUM, MALARIAE
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14
Q

the s/sx happens one after the other called??

A

paroxysm

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15
Q

diagnostic test for malaria

A

peripheral blood smear

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16
Q

2 types of peripheral blood smear

A

thick peripheral blood smear
thin peripheral blood smear

17
Q

when do peripheral blood smear taken?

A

blood sample will be taken at the height of fever (3rd day)

18
Q

discuss thick peripheral blood smear

A
  • quantitative data
  • concerned with the number of parasites in the blood of an infected person
19
Q

discuss thin peripheral blood smear

A
  • qualitative data
  • determines exact parasite/ protozoan present in the blood
20
Q

what are the recommended antimalaria drugs

A

chloroquine
quinine
sulfadoxine
tetracycline
artemisin
mefloquine

21
Q

DOC for drug resistance

A

sulfadoxine ( plasmodium falciparum)

22
Q

for better effectiveness of sulfadoxine, what drug is to combine??

A

pyrimethanine

23
Q

chloroquine (aralen)

A

o 250 mgs
o Visiting to area where there is malaria, you can take this 1-2 week before
o Safe to take during pregnancy

24
Q

quinine

A

o 300 mg
o Given during Emergency situations
o WOF: neurologic toxicity (disorientation, confusion, muscle weakness and worst are convulsions/seizures and coma)

25
Q

Tetracycline

A

Teratogenic (take with straw = permanent straining)

26
Q

management for malaria

A
  1. TSB and antipyretics
  2. Increase fluid intake (3-4L per day)
  3. Monitor V/S and signs of bleeding
  4. Monitor fluid and electrolyte balance
  5. Maintain bed rest until the fever and other symptoms have ceased
  6. Encourage iron-rich, Vit C
27
Q

PREVENTION!! (malaria)(enumerate all)

A
  • on stream cleaning of vegetation
  • larvivorous fish propagation: construction of bioponds
  • 2-4 fish/sqm for immediate impact
  • 200-400 fish/ha: delayed effect
  • avoid peak biting hours: 9pm-3am
  • Zoo prophylaxis: the typing of domestic animals
  • planting of neem tree and other herbal plants
  • long sleeves
  • mosquito nets
  • mosquito repellants
28
Q

PREVENTION!! (malaria)(enumerate all)

A
  • on stream cleaning of vegetation
  • larvivorous fish propagation: construction of bioponds
  • 2-4 fish/sqm for immediate impact
  • 200-400 fish/ha: delayed effect
  • avoid peak biting hours: 9pm-3am
  • Zoo prophylaxis: the typing of domestic animals
  • planting of neem tree and other herbal plants
  • long sleeves
  • mosquito nets
  • mosquito repellants