Membranes 🧋 Flashcards

1
Q

What is the roles of membranes

A

Compartmentalise
Signalling (detect change in environment)
Controlling transporting

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2
Q

How does phospholipid structure aid cell membrane

A

Acts as a barrier, stops water soluble molecules from leaking out and getting in unwanted

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3
Q

how to phospholipids contribute to membrane formation

A

aqueous environment means heads point outward creating bi layre

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4
Q

what type of reaction holds bilayer toghether

A

weak hydrophobic reactions between tails

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5
Q

how is fluidity beneficial to membrane function

A

allows for spontaneous breaking and reforming of membranes

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6
Q

how thick is the bilayre

A

approximately 7.5 nm

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7
Q

how do unsaturated fatty acid tails effect membranes

A

make it less stable and more fluid as less packed togheter

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8
Q

when would unsaturated fatty acid tails be useful

A

in extreme environments

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9
Q

why do phospolidips get chemically modified

A

to act as signalling molecules

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10
Q

how art phospilids chemically modified

A

moving within bilayer to activate other molecules
or being hydrolysed which releases smaller water soluble molecules that bind to specific receptors in cytoplasm

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11
Q

role of glycolipids

A

maintain stability of cell membrane and to facilitate cellular recognition

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12
Q

what do glycolipids act as

A

cell markers or antigens that can be recognised by immune cells

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13
Q

impact of shorter fatty acids

A

increase fluidity, less viscous

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14
Q

why are phospholipids fluid

A

due to them being in constant movement relative to one another

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15
Q

what is the fluid mosaic model

A

phospholipids free to move, creat viscous layre, proteins randomly arranged in bilayer, free to move within layre relative to each other

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16
Q

intergal (transmembrane proteins)

A

permantely attached and span across bilayer

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17
Q

peripheral proteins

A

temporarily attached and associate with surface of membrane

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18
Q

what structure do transmembrane proteins adopt

A

single helical or beta barrels forming channels

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19
Q

glycoproteins

A

intrinsic proteins with a carbohydrate attached, have a role in adhesion and signal transduction

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20
Q

how do glycoproteins act as a receptor

A

binding site for chemical signal

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21
Q

cholesterol

A

maintains integrity and mechanical stability

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22
Q

how does cholesterol affect fluidity

A

binds to fatty acid tail increasing packing of the membrane therefore reducing fluidity of membrane

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23
Q

what does cholesterol make membranes less permeable to

A

very small water soluble molecules that would otherwise pass freely

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24
Q

active transport

A

low to high conc active process requiring atp

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25
active transport step 1
molecule binds to receptor in channel of carrier protein outside cell, inside cell atp binds to carrier protein and is hydrolysed
26
active transport step 2
binding of phosphate molecule to carrier protein causes protein to change shape, molecule is then realesed inside of cell
27
active transport step 3
phosphate molecule is realesed from carrier protein and recombines with adp to form atp, so carrier protein returns to original shape
28
is active transport selective
yes, specific substances are transported by specific carrier proteins
29
bulk transport
active movement of large molecules
30
endocytosis
is bulk transport of materials into cells
31
phagocytosis
endocytosis for solids
32
pinocytosis
endocytosis for liquids
33
endocytosis process
cell surface membrane invaginates when it comes into contact with material, membrane unfolds intill fuses forming a vesicle, which pinches off and moves into cytoplasm for further processing inside cell
34
exocytosis
vesicles move towards and fuse with cell surface membrane, contents of vesicle then realised outside of cell
35
energy in diffusion
particles have KE so movement is random and unequal, particles collides slowing process down, not requiring energy as would be supplied to slowly
36
facilitated diffusion
movement down a gradient across a membrane through protein channels
37
can polar molecules travel through
no except for water as its so small
38
can non polar molecules travel through
yes, but large polar ions cannot pass through
39
can ions pass through
no
40
carrier proteins
integral glycoproteins which bind to a solute and undergo change of shape, only bind to specific molecule, can go against conc gradient using atp
41
which form of protein transport is slower
carrier protein 1000 molecules per second
42
channel proteins
intergral lipoproteins, with fixed shape. only go along conc gradient
43
what do channel proteins transport
ions and they are ion selective
44
effect of alcohol
dissolve membrane, disrupting cells. membrane becomes more permeable and fluid and interactions cannot happen as normal
45
effect of hot tempetures
more KE and move more, so membrane becomes more fluid and loses structure. proteins denature at high temps and if temp increases cell will completely break down
46
effect of cold temps
water expands and ice crystals can pierce membranes, proteins can deform, permeability of membrane increases
47
what helps to regulate membranes in hot temps
cholesterol which regulates membrane fluidity at high temps stabilising membrane and raising melting point
48
solute
substance dissolves in solent to form a solution
49
concentration
mass os solute in given volume of aqueous solution
50
hypotonic
lower solute than ...
51
hypertonic
higher solute than
52
isotonic
same levels of solute
53
what is water potential
pressure created by water molecules as they collide with membrane or container units : kPa
54
water potential of pure water
o kPa which is highest value
55
what do solutes do to w.p
reduce it
56
water potential in plant cells
w.p = solute potential + pressure potential
57
water potential in animal cells
water potential = solute potential
58
cytolysis
cell full of water then burst as cell surface membrane unable to stretch
59
crenation
cell shrinks as water moves out of cell
60
turgor pressure
pressur exerted on cell wall when cell full of water
61
plasmolyse
plant cell protoplast shrinks and pulls away fro cell wall