Melanoma Flashcards

1
Q

Terapia melanoma metastatico

A

BRAF mutato: VEMURAFENIB

C-kit mutato: imatinib, nilotinib,
Esatinib

Wild tipe: IPILINUMAB + CT

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2
Q

Mutazioni melanoma

A
BRAF 50-70% (sotto i 55 anni)
NRAS 15-30% (sopra i 55 anni)
C-kit 15% (sopra i 55 anni)
CDKN2A 10%
PTEN 10%
P53 10%
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