meiosis SDL Flashcards

1
Q

what is meiosis

A

a form of nuclear division occuring in germ cells (become gametes)

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2
Q

what is the difference between meiosis and mitosis

A

Mitosis produces two identical diploid cells and is involved in growth and maintenance, while meiosis produces four genetically diverse haploid cells and is involved in reproduction.

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3
Q

what are the phases of the cell cycle

A

mitotic
- prophase
- metaphase
- anaphase
- telophase

G1 phase
S phase
G2 phase

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4
Q

what are the phases oh mitosis

A
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5
Q

what occurs during the first meiotic division

A

DNA replication
- prophase 1
- metaphase 1
- anaphase 1
- telophase 1

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6
Q

what occurs during the second meiotic division

A

no DNA replication
- prophase 2
- metaphase 2
- anaphase 2
- telophase 2

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7
Q

what occurs during prophase 1

A
  • nucleolus shrinks
  • centroles migrate to opposite poles
  • spindle forms (green, nucleus blue)
  • chromosomes condense
  • homologous chromosomes undergo synapsis and lie together to form a bivalent structure
  • homologous chromosomes interlink
  • chiasmata forms
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8
Q

what are the 5 stages of prophase 1

A
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9
Q

what occurs during metaphase 1

A
  • Nuclear envelope disappears
  • Homologous chromosomes move to equator of spindle (blue; spindle green)
  • Centromeres of each bivalent chromosome orientate to opposite poles
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10
Q

what occurs during anaphase 1

A
  • homologous chromosomes separate and migrate to opposite poles of the spindle
  • one chromosome with 2 chromatids arrives at each pole
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11
Q

what occurs during telophase 1

A
  • cytoplasmic division starts
  • spindle breaks down
  • nuclear envelope & nucleoli form
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12
Q

what occurs during prophase 2

A
  • centrioles replicate & migrate to poles
  • new spindle forms at right angles to previous one
  • Non DNA replication!
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13
Q

what occurs during metaphase 2

A
  • chromosomes move to the equator of the spindle
  • chromatids orientate to opposite poles
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14
Q

what happens during anaphase 2

A
  • chromatids separate and move apart to poles
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15
Q

what happens during telophase 2

A
  • spindle disappears
  • nuclear envelope & nucleoli form
  • chromosomes become thread like
    then cytoplasmic division
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16
Q

discuss spermatogenesis in terms of meiotic division

A

During spermatogenesis the primary spermatocyte in the testis undergoes the first meiotic division to form secondary spermatocytes which then undergo the 2nd division to form spermatids. Finally the spermatids differentiate into spermatozoa.
Meiosis 1: genetic diversity (crossing over)
Meiosis 2: hapoid gametes
[5 stages of meiotic prophase; pre-leptotene, leptotene, zygotene, pachytene and diplotene]

During oogenesis, the primary oocyte undergoes the first meiotic division to give a secondary oocyte and first polar body comtaining half the chromosomes. The secong meioic division then results in a single haploid ovum and a second polar body. So the polar bodies are packages of chromosomes that are not used any further and this is where oogenesis differs from spermatogenesis.

17
Q

discuss meitoci division during oogenesis

A
18
Q

through which methods does genetic variation occur to contribute to evolution

A
  • independent assortment of chromosomes
  • recombination
  • mutation
19
Q

how many mature gametes are produced from one complete meiotic division in oogenesis

A

one mature egg cell

20
Q

discuss gene dosage compenation in females

A
21
Q

list possible errors that can occur during meiosis

A
  • somatic mutations can cause disease but cannot be passed to next generations
  • germ line mutations can be passed on
  • germ line mutations contribute to genetic variation but also can cause genetic disorders
  • chromosomes can remain linked together leading to abnormal number of chromosomes
  • aneuploidy results from the fertilization of gametes in which non-disjunction occured = abnormal number of a particular chromosome

chromosomal disorders effect fertility of cause disease

22
Q

tortoise shell cats have which genetic defect

A

the result of an extra chromosome in a male, producing XXY individuals - meaning most of them are infertile (if they have XXY

23
Q

At what stage do primary oocytes remain arrested until puberty?

A

prophase 1