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Medicine👩🏼‍⚕️🩺 > Medicines💊 > Flashcards

Medicines💊 Flashcards

1
Q

What type of antibiotic is erythromycin?

A

Macrolide

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2
Q

MOA of macrolides?

A

Inhibits 50S subunit assembly

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3
Q

Name 2 ototoxic medications

A

Furosemide and aminoglycosides (e.g. gentamicin)

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4
Q

What EAR side effect can furosemide cause?

A

Sudden bilateral hearing loss

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5
Q

Side effect of statins

A

Myositis
LFT abnormalities

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6
Q

Side effect of corticosteroids

A

Osteoporosis
Glucose changes

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7
Q

Drugs that can cause hyperkalaemia (3)

A

ACEi
Spironolactone
Eplerenone

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8
Q

Drugs causing hypokalaemia (3)

A

Loop & thiazide diuretics
High dose bronchodilators
Mineralocorticoids

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9
Q

A drug that can increase serum warfarin

A

Sodium valproate - cytochrome P450 inhibitor

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10
Q

Side effects of omeprazole (3)

A

Increased risk of C.diff
B12 deficiency
Hypomagnesemia

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11
Q

Significant interactions of omeprazole

A

Reduces clopidogrel (inhibits CYP2C19)
Increases warfarin

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12
Q

MOA of ranitidine

A

Blocks H2 receptors in gastric parietal cells - reduces acid secretion

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13
Q

MOA domperidone

A

Increases gastric motility - blocks D2 receptors

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14
Q

Side effects of domperidone

A

Long QT
Risk of arrhythmia

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15
Q

Why use domperidone?

A

Gastroparesis
N & V

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16
Q

MOA metoclopramide

A

Blocks dopamine D2 receptors, increases gastric emptying

17
Q

Side effects of metoclopramide (3)

A

Extrapyramidal symptoms
Drowsiness
Long QT

18
Q

Contraindication to metoclopramide

A

Parkinson’s

19
Q

MOA loperamide

A

Opioid receptor agonist - reduces peristalsis & increases stool transit

20
Q

When to avoid loperamide

A

C.diff
Bacterial gastroenteritis

21
Q

MOA Senna

A

Stimulant laxative - stimulates enteric nerves

22
Q

Side effects of Senna

A

Abdominal cramping
Diarrhoea
Hypokalaemia (chronic use)

23
Q

MOA lactulose

A

Osmotic laxative & ammonia reducer

Non-absorbable sugar drawing water into colon

24
Q

MOA mesalazine

A

Prostaglandin inhibitor

25
Q

Side effects mesalazine (3)

A

Nephrotoxicity
Pancreatitis
Hypersensitivity reaction

26
Q

Drugs used with caution with mesalazine

A

NSAIDs

27
Q

MOA prednisolone

A

Binds glucocortitcoid receptors

28
Q

Side effects prednisolone (4)
CHIO

A

Osteoporosis
Hyperglycaemia
Immunosuppression
Cushing features

29
Q

Monitoring with prednisolone (3)

A

Blood glucose
Bone density
Adrenal suppression (chronic)

30
Q

Interactions with prednisolone (2)

A

NSAIDs - ulcers
Live Vaccines - immunosuppression

31
Q

MOA ondansetron

A

Blocks 5HT3 receptors

32
Q

Side effects ondansetron

A

Long QT
Constipation
Headache

33
Q
A

Medicine👩🏼‍⚕️🩺 (23 decks)

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