Endocrine🍬

Question 1

Diagnostic test for Addisons disease

Answer 1

Short synacthen test

Question 2

Type of parathyroidism caused in CKD?

Answer 2

Secondary

Question 3

Treatment for Grave’s in first trimester

Answer 3

Propylthiouracil

Question 4

Long term management of Addison’s

Answer 4

Cortisol and aldosterone replacement: hydrocortisone and fludrocortisone

Question 5

Hypocalcaemia ECG change

Answer 5

Prolonged QT interval

Question 6

Management of secondary hyperparathyroidism in CKD

Answer 6

Vitamin D analogues and phosphate binders

Question 7

HLA associated to T1DM

Answer 7

HLA-DR3

Question 8

First line anti thyroid medication

Answer 8

Carbimazole

Question 9

Serious complication of rapid correction of hyponatraemia

Answer 9

myelinolysis

Question 10

Why should hypernatraemia be corrected slowly?

Answer 10

Avoid cerebral oedema

Question 11

HbA1c level for diagnosis of diabetes

Answer 11

> 48

Question 12

Fasting plasma glucose for diabetes diagnosis

Answer 12

> 7

Question 13

Long term treatment for T1DM

Answer 13

Insulin

Question 14

Diabetes drug with cardiovascular and renal benefits

Answer 14

Empagliflozin (SGLT 2 inhibitor)

Question 15

HLA genotype associated to T1DM

Answer 15

HLA DR3

Question 16

2nd line diabetes medication after metformin in patients with CV risk or CKD

Answer 16

SGLT 2 inhibitor e.g. empagliflozin

Question 17

2nd line T2DM medication in patients with no contraindications

Answer 17

DPP4 inhibitor - Sitagliptin

OR sulfonylurea - Gliclazide

Question 18

Initial fixed-rate insulin infusion dose in DKA

Answer 18

0.1 units/kg/hour

Question 19

Key indicator test result for T1DM

Answer 19

Low serum C peptide

Question 20

First line treatment for De Quervain’s thyroiditis

Answer 20

NSAIDs

Question 21

What hormone changes in Conn’s?

Answer 21

Increased aldosterone

Question 22

Metabolic imbalance in Conn’s

Answer 22

Hypokalaemia

Question 23

MOA spironolactone

Answer 23

Aldosterone antagonist - potassium sparing diuretic

Question 24

Initial management of a pheochromocytoma

Answer 24

Alpha blocker - to create alpha blockade

Question 25

Electrolyte abnormality in Cushing’s

Answer 25

Hypokalaemic metabolic alkalosis

Question 26

Drug used for gastroparesis from DM

Answer 26

Domperidone

Question 27

Important blood result for Wilson’s disease

Answer 27

Low serum caeruloplasmin

Question 28

Important blood results for haemachromatosis

Answer 28

Transferrin >45%

Question 29

SSRIs can cause what syndrome

Answer 29

SIADH