Endocrine🍬 Flashcards
Diagnostic test for Addisons disease
Short synacthen test
Type of parathyroidism caused in CKD?
Secondary
Treatment for Grave’s in first trimester
Propylthiouracil
Long term management of Addison’s
Cortisol and aldosterone replacement: hydrocortisone and fludrocortisone
Hypocalcaemia ECG change
Prolonged QT interval
Management of secondary hyperparathyroidism in CKD
Vitamin D analogues and phosphate binders
HLA associated to T1DM
HLA-DR3
First line anti thyroid medication
Carbimazole
Serious complication of rapid correction of hyponatraemia
myelinolysis
Why should hypernatraemia be corrected slowly?
Avoid cerebral oedema
HbA1c level for diagnosis of diabetes
> 48
Fasting plasma glucose for diabetes diagnosis
> 7
Long term treatment for T1DM
Insulin
Diabetes drug with cardiovascular and renal benefits
Empagliflozin (SGLT 2 inhibitor)
HLA genotype associated to T1DM
HLA DR3
2nd line diabetes medication after metformin in patients with CV risk or CKD
SGLT 2 inhibitor e.g. empagliflozin
2nd line T2DM medication in patients with no contraindications
DPP4 inhibitor - Sitagliptin
OR sulfonylurea - Gliclazide
Initial fixed-rate insulin infusion dose in DKA
0.1 units/kg/hour
Key indicator test result for T1DM
Low serum C peptide
First line treatment for De Quervain’s thyroiditis
NSAIDs
What hormone changes in Conn’s?
Increased aldosterone
Metabolic imbalance in Conn’s
Hypokalaemia
MOA spironolactone
Aldosterone antagonist - potassium sparing diuretic
Initial management of a pheochromocytoma
Alpha blocker - to create alpha blockade
Electrolyte abnormality in Cushing’s
Hypokalaemic metabolic alkalosis
Drug used for gastroparesis from DM
Domperidone
Important blood result for Wilson’s disease
Low serum caeruloplasmin
Important blood results for haemachromatosis
Transferrin >45%
SSRIs can cause what syndrome
SIADH
