Anaesthetics & Peri Op💉 Flashcards
4 NSAIDs
Ibuprofen
Diclofenac
Aspirin
Naproxen
Side effects of NSAIDs (2)
Gastric irritation
Renal impairment
3 drug interactions with NSAIDs
Warfarin
Heparin
Lithium
Side effects of opioids (5)
Respiratory depression
N & V
Sedation
Bradycardia
Constipation
Side effects of amitriptyline (5)
Dizziness
Drowsiness
Dry mouth
Constipation
Urinary retention
MOA of gabapentin
Calcium channel blocker
Analgesia to avoid in renal impairment (2)
Morphine
NSAIDs - dose dependant
Safe analgesia in renal impairment (5)
Paracetamol
Oxycodone
Buprenorphine
Fentanyl
Ketamine
Analgesia caution in liver disease (2)
Paracetamol, methadone
Agent to reduce ICP in emergency neurosurgical induction
Thiopental sodium
Analgesic which can increase ICP
Ketamine
Anaesthetic which can cause malignant hyperthermia (2)
Sevoflurane and isoflurane
Suxamethonium
3 signs of malignant hyperthermia
Muscle rigidity
Hyperthermia
Skin mottling
Common side effect of ketamine
Increased salivation and secretions
Treatment of local anaesthetic toxicity
IV lipid emulsion
Rocuronium is often used for…
Rapid sequence induction
Example of a non-depolarising muscle relaxant
Rocuronium
1st line management malignant hyperthermia
IV dantrolene
How to manage insulin before elective surgery
Reduce the once daily long acting dose by 20% day before
Preferred induction agent in patients with CV problems
Etomidate
Induction agent for trauma patients with haemodynamic instability
Ketamine
Induction agent to avoid in adrenal insufficiency
Etomidate
Common side effect of propofol
Pain at injection site
Why is PEEP useful in RSI
Reduces risk of atelectasis
What to do with warfarin before surgery
Stop 5 days before, have LMWH to bridge
What to do with apixaban before surgery
Discontinue 2 days before
What can propofol do to BP during induction
Hypotension - due to vasodilation
What is type 1 hypersensitivity
IgE mediated
What is type 2 hypersensitivity
Cytotoxic - antibody mediated
What is type 3 hypersensitivity
Immune complex - antibody-antigen complex
What is type 4 hypersensitivity
Delayed - T-cell mediated
Example of Type 3 hypersensitivity (3)
SLE
Rheumatoid arthritis
Post-strep glomerulonephritis
