Gastroenterology💩 Flashcards

1
Q

Most common causative organism of travellers diarrhoea

A

E. Coli

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2
Q

Score used to assess severity of chronic liver disease for liver transplant consideration

A

MELD score

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3
Q

What is the MELD score used for

A

To assess severity of chronic liver disease to prioritise for liver transplant

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4
Q

What tests are normal in biliary colic?

A

Normal LFTs and inflammatory markers

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5
Q

Antibody associated to PBC

A

AMA

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6
Q

HNPCC increases risk of what other malignancies (3)

A

Endometrial, ovarian, gastric

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7
Q

1st line treatment for Crohn’s exacerbation

A

Prednisolone

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8
Q

Class 1 obesity BMI range

A

30-34.9

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9
Q

Grading tool for cirrhosis severity

A

Child-Pugh score

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10
Q

What does incarceration of a hernia mean

A

When it is irreducible without compromising blood supply

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11
Q

Pathogen in acute cholangitis

A

E. Coli

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12
Q

What does aldosterone do to sodium

A

Increases sodium reabsorption

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13
Q

Crucial vitamin supplements for alcoholic liver disease

A

B vitamins

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14
Q

Investigation to do AFTER confirming cortisol levels in Cushing’s

A

ACTH level

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15
Q

Why do we do ACTH level after a cortisol test for Cushing’s

A

Differentiate between ACTH-dependant and ACTH-independent

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16
Q

2 signs which point towards B12 deficiency

A

Glossitis (red swollen tongue)
Subtle neurological signs

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17
Q

Hypocalcaemia causes what ECG change

A

Long QT

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18
Q

First line management Grave’s disease

A

Carbimazole

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19
Q

What symptom differentiates external vs internal haemorrhoids

A

External are painful

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20
Q

Most significant risk factor for oesophageal SCC

A

Tobacco smoking

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21
Q

Most common cause of B12 deficiency

A

Pernicious anaemia

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22
Q

Type of anaemia that causes B12 deficiency

A

Pernicious

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23
Q

Physiology of pernicious anaemia

A

Autoimmune, destroys gastric parietal cells, leading to lack of intrinsic factor

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24
Q

Cholestatic liver function markers

A

Elevated bilirubin, ALP and GGT

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25
PSC finding on MRCP
Multiple bile duct strictures with ‘beaded’ appearance
26
Best management for symptomatic primary hyperparathyroidism
Parathyroidectomy
27
First line investigation acute pancreatitis
Serum lipase
28
Best test to diagnose hiatus hernia
Barium swallow
29
What metabolic imbalance is caused by Cushing’s
Hypokalaemic metabolic acidosis
30
Route of transmission for Hep A
Faecal-oral
31
Treatment for level 2 haemorrhoids
Rubber band ligation
32
First line treatment for itching in PBC
Cholestyramine
33
Drug to maintain remission in Crohn’s
Azathioprine
34
Diagnostic test for diverticulitis
CT abdo and pelvis with contrast
35
Surgical option for rectal tumour >8cm from anal margin
Anterior resection
36
What skin disease is associated to coeliac?
Dermatitis herpetiformis
37
What is a good blood indicator of ischaemia
Lactate
38
First line treatment for dermatitis herpetiformis
Dapsone - stops itching
39
Antibiotic for cholera
Doxycycline
40
Antibiotic prophylaxis before endoscopy in GI bleeds
Ceftriaxone
41
Goblet cells in Chrohn's disease are...
Increased
42
Antibodies elevated in B12 deficiency
Intrinsic factor antibodies
43
1st line treatment for mild/moderate ulcerative colitis flare
Rectal mesalazine
44
What does positive Anti-HBsAg imply
Acute Hep B
45
What does Anti-HBs imply
Hep B immunity
46
Management of severe ulcerative colitis flare
IV hydrocortisone
47
What metabolic change can PPIs cause
Hyponatraemia
48
Test for H.pylori post-eradication
Urea breath test
49
What is the best test to monitor acute liver failure
Prothrombin time
50
How to differentiate between type 1 and 2 hepatorenal syndrome
Type 1 happens rapidly
51
Antibodies associated with PBC
AMA Serum IgM raised
52
First line management PBC
Ursodeoxycholic acid
53
PPIs can cause ____natraemia
Hyponatraemia
54
First line antibiotic for normal C.diff infection
Oral vancomycin
55
Antibiotics for life-threatening C.diff infection
Oral vancomycin & IV metronidazole
56
Iron study results for haemochromatosis - transferrin, ferritin, TIBC
High transferrin High ferritin TIBC low
57
% weight loss over ? time to diagnose malnutrition
>10% over 6 months
58
Most common organism in SBP - spontaneous bacterial peritonitis
E.coli
59
What happens to cells in Barrett’s oesophagus?
Squamous cell epithelium is replaced by columnar
60
Inflammatory condition associated to ulcerative colitis
PSC
61
Treatment of recurrent C.diff infection within 12 weeks of previous symptom resolution
Fidaxomicin
62
When do we use fidaxomicin for C.diff?
Within 12 weeks of prev. Symptom resolution
63
The M rule for PBC
IgM AMA M2 subtype Middle aged females
64
What portion of bowel is most commonly affected by Crohn’s
Ileum
65
Management of severe alcoholic hepatitis
Prednisolone
66
Wilson’s disease management
Penicilliamine
67
What cancer is a complication of PSC?
Cholangiocarcinoma
68
What type of diet should people with Ascites have
Low sodium
69
AST:ALT ratio in alcoholic hepatitis
2:1
70
What would SAAG >11 suggest
Cause of ascites is due to raised portal pressure
71
What would SAAG < 11 suggest
Ascites NOT due to portal hypertension E.g. TB, pancreatitis, nephrotic syndrome
72
Triad for Wernicke’s encephalopathy
Confusion Opthalmoplegia Ataxia
73
What deficiency is in Wernicke’s encephalopathy
Thiamine - B1
74
When (in hours) does delirium tremens occur
48-72 hours from alcohol withdrawal
75
Electrolyte imbalance in diarrhoea - anion gap, ? / ?
Normal anion gap Metabolic acidosis