Male Reproduction Flashcards
how often does pulsatile release occur?
8-14x per day
when does pulsatile release begin and end?
puberty until death
pulsatile release
hypothalamus releases ____ which stimulates the anterior pituitary to release ____
GnRH
LH & FSH
How is testosterone production stimulated?
LH stimulates interstitial cells of Leydig to release androgens (DHEA & androstenodeione)
-> testosterone released
function of testosterone
primary & secondary characteristics of male adults
- body hair distribution
- voice: hypertrophy of laryngeal mucosa & larynx
- skin: thickens skin
- increase ruggedness of subcutaneous tissues
- sebaceous glands & oil production
- muscle development
- bone growth & Ca retention: inhibits production of osteoclasts
- RBCs: increase erythropoeitin - RBC production
- stimulates Na & water reabsorption in PT of kidney
testosterone is converted to DHT by the enzyme ____
5a reductase
functions of DHT
- fetal development of penis, penile urethra, scrotum, prostate
- pubertal growth of scrotum, prostate, sexual hair, sebaceous glands
- prostatic secretion
testosterone is converted to estradiol by ____, especially in ____
enzymes in peripheral adipose tissue
liver & breast
high levels of estradiol in men can lead to…
benign prostatic hypertrophy & possibly prostate cancer
FSH stimulates…
sertoli cells of seminiferous tubules to produce sperm & inhibin
Very early in development, testosterone is formed within the male embryo. What is the function of this hormone at this stage of development?
Stimulation of development of male sex organs
