Gas Transport Flashcards
what is the Bohr effect?
CO2 replaces O2 on the hemoglobin at the tissue (shift O2-Hb dissociation curve to the right)
what is the Haldane effect?
O2 replaces CO2 on the hemoglobin in the lungs (shift O2-Hb dissociation curve to the left)
what is the PO2 for oxygenated blood leaving the lungs?
104
what is the PO2 for reduced blood returning to the lungs from the tissues?
40
what factors can cause a shift of the O2-Hb curve to the right?
increased H+ (pH)
increased CO2
increased temperature
increased 2,3 BPG
what does it mean if the O2-Hb curve shifts to the right?
O2 falls off of Hb sooner
what scenario would cause a shift of the O2-Hb curve to the right?
exercise
what factors can cause a shift of the O2-Hb curve to the left?
decreased H+ (pH)
decreased CO2
decreased temperature
what does it mean if the O2-Hb curve shifts to the left
oxygen binds to Hb faster
if the O2-Hb curve shifts to the right, where is it located?
tissue
(O2 from blood into tissue)
if the O2-Hb curve shifts to the left, where is it located?
lungs
how is 70% of CO2 transported?
as bicarbonate ion + Hydrogen ion (HCO3 + H+)
how is 23% of CO2 transported?
as carbaminohemoglobin (HbCO2)
how is 7% of CO2 transported?
dissolved gas
how is 98.5% of O2 transported?
bound to hemoglobin