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BIO 130.01 > M1: Linkage and Sex Determination > Flashcards

M1: Linkage and Sex Determination Flashcards

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Biology 101 flashcards
1
Q

Genes located in the same chromosome (linear order)

A

Linked Genes

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2
Q

Produces only parental gametes in equal proportions

A

Complete Linkage

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3
Q

Evidence of linkage to one another

A

Linkage group

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4
Q

Estimation of distance between two genes or loci along the chromosome.

A

Chromosome Mapping

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5
Q

Percent Recombination and Crossing Over

A

Directly Proportional

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6
Q

Estimates the genetic distance between genes

A

Genetic Map

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7
Q

Specifies the physical location and distance between genes

A

Physical Map

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8
Q

Chromosomes are distinguish between banding patterns and sizes

A

Cytological Map

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9
Q

Significance of Chromosome Mapping

A
  • difference between species
  • understanding segregation and inheritance of genes
  • insight to gene function
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10
Q

They developed “crossing over as basis of distance between genes”

A

Thomas Hunt Morgan & Alfred Sturtevant

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11
Q

Similar to parents or parental gamete

A

Non-Crossingover Gametes

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12
Q

Exchange between non-sister chromatids in a single tetrad

A

Single Crossover

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13
Q

Two or more exchanges between non-sister chromatids in a single tetrad

A

Multiple Crossover

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14
Q

Two separate and independent exchanges must occur simultaneously

A

Double Crossovers

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15
Q

Conditions for Three-Point Mapping

A
  1. Heterozygous in all loci
  2. Phenotypes of resulting offspring must be observed
  3. Number of offspring must represent crossover classes
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16
Q

A crossover event in one region of the chromosome inhibits a second event in nearby regions

A

Interference

17
Q

Ratio of observed double crossovers to expected crossovers

A

Coefficient of Coincidence

18
Q

Formula for Coefficient of Coincidence (C)

A

DCO-observed/DCO-expected

19
Q

Formula for Interference

A

1-C

20
Q

DCO-observed = DCO-expected

A

No Interference

21
Q

DCO-observed > DCO-expected

A

Negative Interference

22
Q

DCO-observed < DCO-expected

A

Positive Interference

BIO 130.01 (8 decks)

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