Lympatic System #2

Question 1

disease similar to smallpox but less virulent

Answer 1

cowpox

Question 2

ability to cause disease

Answer 2

virulence

Question 3

Person is exposed by normal contact and is infected

Answer 3

naturally acquired active immunity

Question 4

Transplacental transfer is an example of

Answer 4

Naturally acquire passive immunity

Question 5

What is passed in the breast milk that contains antibodies?

Answer 5

colostrum

Question 6

A vaccine is an example of

Answer 6

artificially acquired active immunity

Question 7

Transfer of humoral antibodies like antivenin

Answer 7

artificially acquired passive immunity

Question 8

What does the latent period before measurable amounts of specific antibodies appear and how long does it take?

Answer 8

5-10 days primary response

Question 9

Subsequent exposure of one person to the same antigen results in _____ produced by _______

Answer 9

secondary response, B cells (memory cells)

Question 10

The ability of B cells to inherit the ability to produce specific antibodies explains

Answer 10

clonal selection theory

Question 11

Most abundant lymphocytes in an adult

Answer 11

memory t cells

Question 12

How does a germinal center develop?

Answer 12

From a B cell that has been stimulated by an antigen and activated by Helper T cell

Question 13

Proliferating B cells in a germinal center under go ______ which generates a diversity of new antibodies

Answer 13

somatic hypermutation

Question 14

Develop of a secondary response provides ____ against specific pathogens

Answer 14

active immunity

Question 15

The first successful polio vaccine

Answer 15

the salk vaccine

Question 16

oral vaccine that used to cause polio

Answer 16

sabin

Question 17

What 3 ways can vaccines be produced

Answer 17

live viruses with weakened virulence, killed viruses, recombinant viral proteins

Question 18

molecules that can boost the immune response when delivered with the vaccine

Answer 18

adjuvants

Question 19

adjuvants work because dendritic cells have ____ receptors that bind to what?

Answer 19

pattern recognition recepters, pathogen associated molecular patters and damage associated molecular patterns

Question 20

Thyroglobin in the thyroid is an example of a

Answer 20

immunilogically privelaged site

Question 21

antibodies made against self antigens are called

Answer 21

autoantibodies

Question 22

Killer T cells that attck self antigens are called

Answer 22

autoreactive T cells

Question 23

The two mechanisms of immunological tolerance

Answer 23

clonal deletion and clonal anergy

Question 24

autoimmune disease may occur because of

Answer 24

failure of t regulatory cells

Question 25

the ability of mount a specific immune response that does not occur until a month after birth

Answer 25

immunological competence

Question 26

What creates the great IgG diversity in intravenous immunoglobulin therapy?

Answer 26

plasma taken from many different people

Question 27

animal injected with an antigen are used to obtain _______

Answer 27

monoclonal antibodies

Question 28

B lymphocytes combined with a cancerous myeloma cell in vitra produces a

Answer 28

hybridoma

Question 29

Drug used to treat non hodgekins lymphoma

Answer 29

rituximab

Question 30

Blocks binding of vascular endothelial growth factor and treats what

Answer 30

Avastin (bevacizumab), colorectal, lung, kidney and brain cancer

Question 31

Harvesting patients T cells to combat cancer

Answer 31

adoptive cell transfer

Question 32

Treatment used specifically for melanomas

Answer 32

Tumor infiltrating lymphocyte therapy

Question 33

What happens in chimeric antigen receptor therapy?

Answer 33

patient’s own t cells are given artificially created t cell receptor to target tumor antigens

Question 34

natural killer cells are part of the ____ immune system

Answer 34

innate

Question 35

How are natural killer cells like/dislike killer t cells

Answer 35

can destroy cells from cell to cell contact but they also can do with withot prior exposure to foreign antigens

Question 36

Autoantibodies developed against lens protein in a damaged eye may cause destruction of a healthy eye

Answer 36

sympathetic opthalmia

Question 37

autodestruction of the thyroid

Answer 37

hashimoto’s thyroiditis

Question 38

Drug induced thrombocytopenia purpura is an example of

Answer 38

a self antigent hat is usually tolerated but may be altered by combining with a forein antigen

Question 39

IgM antibodies attack IgG antibodies

Answer 39

rheumatoid arthritis

Question 40

What two disorder can occur from antibodies produced in response to streptococcus cross reacting with self antigens?

Answer 40

glomerulonephritis, rheumatic fever

Question 41

What do thyroid cells present in Grave’s disease

Answer 41

class 2 MHC molecules

Question 42

Beta cells of pancreatic islets abnormally producing class 2 MHC molecules

Answer 42

type 1 diabetes

Question 43

Inadequate expression of what gene may lead to autoimmune disease, and why?

Answer 43

FOXP3, helps convert T lymphocytes to reg T cells

Question 44

Antigen antibody combinations that are free rather than attached to bacterial/other cells

Answer 44

immune complexes

Question 45

What causes the damage to arteries in hepatitis B

Answer 45

immune complex disease (periarteritis)

Question 46

What are rheumatoid factors?

Answer 46

IgM antibodies that bind to the Fc portion of IgG antibodies and create immune complexes

Question 47

What helps diagnose SLE?

Answer 47

antinuclear antibodies (ANA)

Question 48

What usually kills people with SLE

Answer 48

immne comlexes in glomerular capillaries (glomerulonephritis)

Question 49

What surgical procedure initially removed the man’s melanoma in disappearing act?

Answer 49

Moh’s micrographic surgery

Question 50

Treatment that boosts body’s immune system against tumors

Answer 50

interferon alpha therapy

Question 51

What cured Danial?

Answer 51

radiation therapy in his hip, abscopal phenomenom