Luteal Phase - Exam 3 Flashcards
Lasts from the time of ovulation until Luteolysis
Luteal phase
Regression of the CL
Luteolysis
Luteal phase consists of what types of estrus
Metestrus and diestrus
The luteal phase consists of
Corpora lutea formation
Production of progesterone
Luteolysis
At ovulation, the follicles and blood vessels _____ within the follicular wall
Rupture
What does the rupture of follicle and blood vessels form?
The corpus hemorrhagicum (bloody body)
Appear as small, pimple-like structures on surface of ovary
Day 1-3 of estrous cycle
CL begins to increase in size and hemorrhagic appearance
Day 3-5 of estrous cycle
CL gains size until the ____ of the estrous cycle
Middle
CL has reached mature size and is producing maximal levels of progesterone
Diestrus
Luteolysis occurs and CL loses functionality and decreases in size
End of luteal phase
CL degrades and forms
Corpus albicans
Scar-like tissue
Corpus albicans
After ovulation, ____ ________ and _________ _____ undergo dramatic transformation
Theca interna
Granulosal cells
Process whereby cells of the ovulatory follicle are transformed into luteal tissue
Luteinization
Both cell types of luteal tissue are
Steroidogenic
Luteal tissue consists of two cell types:
Large cells
Small cells
Large/small: Originate from Granulosal cells
Large cells
Large/small: Originate from Theca interna cells
Small cells
Large/small: Diameter 20-40 uM
Large cells
Large/small: Diameter <20 uM
Small cells
Large/small: Many dense secretory granules near plasma membrane which contain oxytocin and relaxin
Large cells
CL of estrous cycle
Oxytocin
CL of pregnancy
Relaxin
Large/small: No secretory granules
Small cells
Large/small: Rarely multiple after ovulation
Large cells
Large/small: Few lipid droplets
Large cells
Large/small: Numerous lipid droplets
Small cells
Large/small: Irregular shape
Small cells
Large/small: undergo hyperplasia
Small cells
Large/small: round shape
Large cells
Large/small: undergo hypertrophy
Large cells
Increase in size
Hypertrophy
Increase in number
Hyperplasia
Growth of CL amass is net effect of
Large luteal cells undergo hypertrophy
Small luteal cells undergo hyperplasia
Non-steroidogenic cells also increase in numbers
Hypertrophy in sheep
Volume of large cells increase 3-fold
Hyperplasia in sheep
Number of small cells increases 5-fold
Vigor of CL depends on
Number of luteal cells
Degree to which CL becomes vascularized