Chapter 14 - Exam 4 Flashcards
Mammals with a placenta
Eutherian mammals
Ensures that the developing conceptus will be provided with adequate nutrition and protection during its development
Intrauterine development
Animals which lay eggs
Can’t completely protect eggs from environmental or predatory danger
Oviparous
Final steps of reproduction are
Formation of a placenta
Acquisition of endocrine function of the placenta
Parturition
Transient organ of metabolic interchange between the conceptus and dam
A transient endocrine organ
Produces a variety of hormones
Placenta
The placenta is composed of a ________ component and a ________ component
Fetal
Maternal
Giving birth to young
Final step in reproductive process
Parturition
Parturition is initiated by the
Fetus
Parturition involves complex cascade of endocrine events that promote….
Myometrial contractions
Dilation of cervix
Expulsion of fetus and extra embryonic membranes
Functional unit of the fetal placenta
Chorionic villus
Small, finger-like projections that appear on the surface of the
Chorion
Placentas are classified by distribution of _________ ______ on surface of chorion
Chorionic villi
4 types of placenta:
Diffuse
Cotyledonary
Zonary
Discoid
Type of placenta: uniform distribution and of chorionic villi which cover the surface of the chorion
Sow and mare
Diffuse
Animal placenta: velvet-like surface with many closely spaced chorionic villi
Sow
Animal placenta: many specialized “microzones” of chorionic villi
Mare
Specialized “microzones” of chorionic villi
Microcotyledons
Unique transitory structures of chorionic villi in the mare
Produce eCG
Endometrial cups
Type of placenta: large number of discrete button-like structures (cotyledons)
Unit of placenta of trophoblastic origin consisting of abundant blood vessels and connective tissue
Cotledonary
Type of placenta found in ruminants
Cotyledonary
Type of placenta found in mares and sows
Diffuse
How many Cotyledons does an ewe have
90-100
How many cotyledons does a cow have
70-120
Point of interface between placenta and uterus
Placentome
Placentome consists of
Feral cotyledon
Maternal caruncle
Type of placenta: band like zone in center of placental unit
Zonary
Type of placenta found in dogs and cats
Zonary
Type of zone: highly pigmented ring at either end of central zone
Consists of small hematomas
Unknown function
2nd zone
Type of zone: transparent on distal ends of chorion
Poor vascularity
3rd zone
Type of placenta: either 1 or 2 disc-like structures on the chorion
Discoid
Type of placenta found in humans and rodents
Discoid
4 types of placenta based on number of placental layers
Epitheliochorial
Endotheliochorial
Hemochorial
Hemoendothelial
Least intimate among placental types
Both endometrial epithelium and epithelium of chorionic villi remain intact
7 placental layers
Epitheliochorial
Animals with 7 placental layers (epitheliochorial)
Sow
Mare
Ruminants (cow and ewe)
Subsection of Epitheliochorial
Syndesmochorial
A unique cell type found in the ruminant placenta
Quite large with 2 nuclei
Binucleate giant cells (BNGC)
Binucleate giant cells originate from
Trophoblast cells
Binucleate giant cells secrete
Placental lactogen
Pregnancy specific protein B
Protein unique to ruminants
Pregnancy specific protein B
Complete erosion of endometrial epithelium and surrounding interstitium
Maternal capillaries are directly exposed to epithelial cells of chorion
5 layers
Endotheliochorial
What animals have 5 placental layers (endotheliochorial)
Dogs
Cats
_________ is more intimate than epitheliochorial because there is no ________ _______
Endotheliochorial
Endometrial epithelium
Chorionic epithelium is in direct apposition to maternal pools of blood
Nutrients and gases are exchanged directly from maternal blood and must move through only 3 layers
3 layers
Hemochorial
What animals have 3 placental layers (hemochorial)
Primates
Mice
Most intimate type of placenta
Barriers to waste nutrients and gaseous transfer are almost non-existent
No direct exchange of blood components between fetal and maternal side
1 layer
Hemoendothelial
Animals with 1 placenta layer (hemoendothelial)
Rabbit
Rat
Guinea pig
Placenta regulates exchange between ____ and _____
Fetus
Dam
Placenta mechanism:
Gases and water pass from low to high concentrations
Active transport pumps for sodium, potassium, and calcium
Simple diffusion
Placenta mechanisms:
Simple diffusion
Facilitated diffusion
Active transport
Placenta mechanism: glucose and other metabolically imported materials are transported using carrier molecules
Facilitated diffusion
Major source of energy for the fetus
Glucose
Glucose is most derived from
Maternal circulation
Results from metabolism of body fat, which generates ketones for energy when glucose is limited
Ketosis