Lupus Flashcards
What is the average age for lupus
6 years
Which species is most often affected by lupus
Dogs
What dogs are predisposed to lupus
Shetland sheepdogs
Collies
German Shepard
Old english sheepdog
What is the etiology of lupus
It is a type 3 hypersensitivity reaction. Tags the bodies own tissues for destruction by phagocytes and the complement system.
Which tissues are usually destroyed by lupus
️Glomerulus of the kidney, synovial membrane of joints and skin.
What are common musculoskeletal problems with lupus
Immune complexes cause inflammation of the joints and muscle pain an wasting.
What are common skin problems with lupus
Lesions, depigmentation, alopecia, scaling, ulcers in anus mouth and nostrils
What are common urinary problems with lupus
Glomerulonephritis. enlargement of the kidney or liver
What are common blood/immunity problems caused by lupus
Immune mediated hemolytic anemia. Leukopenia and thrombocytopenia
What is the clinical presentation of lupus
Leg shifting and lameness. Can also show signs of anemia such as pale gums, weakness, black tarry stools and bruising. It can also cause skin lesions, anorexia, lethargy and vomiting.
What tests are used to diagnose lupus
Xray Blood tests Ana titer test Coombs test Skin biopsy
How do you treat lupus
You give immunosuppressive drugs and corticosteroids
What is a more radical form of lupus treatment
Splenectomy
What is lupus
Autoimmune disease where the body attacks its own tissue mistaking it for a foreign invader. The body makes antibodies against its own tissue causing acute inflammation
What is the prognosis for lupus
Over 40% of dogs with lupus are dead within a year either by the disease or from a compassionate euthanasia
