Lupus Flashcards
1
Q
Cause of lupus
A
- exact cause unknown
- autoimmune disease
- genetic predisposition
- hormones
- environment/chemicals
2
Q
what is the presenation of lupus/what systems does it affect
A
- relapsing remitting presentation
- affects autoantibodies, vascular abnormalites, inflammation
3
Q
who does lupus typicaly affect
A
- ages 15-40
- affects women 10-15x more than men
- african american, african caribbean, hispanic-american, american-indian, asian-americans more
4
Q
What are the types of lupus
A
- discoid: skin lesions
- systemic (SLE)
- drug-induced lupus
- antiphospholipid antibody syndrome
- late stage lupus
5
Q
Systems/oragns affected by lupus
A
- skin
- joints
- kidneys
- heart
- blood forming organs
- nervous system
- mucous membranes
- digestive system
6
Q
Most common symptoms of lupus
A
- extreme fatigue
- painful or swollen joints
- unexplained fever
- skin rashs
- kidney problems (most common organ affecte after skin)
7
Q
Most common signs of SLE
A
- constitutional symptoms
- arthralgia
- arthritis
- skin rash
- pulmonary involvment
- anemia
- raynaud’s syndrome
- kidney involvement
- photosensitivity
- hair loss
- nervous system involvement
- mouth, nose, vaginal ulcers
8
Q
Integumentary changes with Lupus
A
- Butterfly rash
- skin rash on extensor surface
- hair changes
- photosensitivity
9
Q
MSK changes with lupus
A
- arthritis
- arthralgia
- fibromyalgia
- may appear chronically ill
10
Q
lupus
cardiovascular and pulmonary systems changes
A
- hemolytic anemia
- pericarditis or endocarditis
- pleural effusion
- thrombocytopenia
- stroke
- DVT/PE
11
Q
lupus neurological invovlement
A
- AKA neuropsychiatric lupus
- high risk of CVA
- cerebrovascular disease
- seizures
- headaches
- anxiety
- cognitive dysfunction
12
Q
lupus
peripheral nervous system involvement
potential assoicated conditions
A
- peripheral neuropathy
- guillian barre syndrome
- acute inflammatory demyelinating polyradiculoneuropathy
- myasthenia gravis
13
Q
How to diagnosis lupus
A
4 signs of
- at least 1 immunologic sign (aka positive ANA test)
- at least 1 clinical sign or symptom
14
Q
medical tx for lupus
A
- NSAIDs
- corticosteriod as needed
- disesase modifying anti-rheumatic drugs
- anticoagulants
15
Q
Prevention of complications in lupus
A
- regular monitoring of heart function
- osteoporosis screening
- up-to-date immunizations
- journaling of signs and symptoms
16
Q
examples of disease modifying anti-rheumatic drugs
A
- antimalarials (plaquenil)
- immunosuppressants (imuran)
- biologic: benlysta (monoclonal antibody)
- methotrexate
17
Q
PT concern ith lupus
A
- exacerbations/flares
- heightened reaction to stress
- recovery time may be different
- pacing
