Lp 67

Question 1

*a.k.a somatotropin
*produced & secreted throughout life
*needed for N growth & various metabolic fxns
*made & secreted in the anterior pituitary thru/out lifecycle
*secreted most during sleep

Answer 1

Growth hormone

Question 2

GH stimulates growth & maintenance of

Answer 2

-ct cartilage
-bone
-skeletal & cardiac m
*visceral organs
*endocrine glands
*skin

Question 3

GH affects metabolism by facilitating

Answer 3

-protein synthesis
-f.a mobilization
-increase beta oxidation
-maintains/ increase blood glucose levels

Question 4

Pituitary lesions

Answer 4

-hypofunctioning
-hyperfunctioning

Question 5

Results of hyper functioning depends on age:

Answer 5

-prior to end of puberty: Gigantism

-after puberty: Acromegaly

Question 6

Many different causes of short stature

Answer 6

-hereditary
-endocrine dysfunction:
*hypothyroidism
*poorly controlled DM
*GH deficiency
-renal insufficiency
-skeletal dysfxn
-emotional deprivation (psychosocial dwarfism)

Question 7

-Increase secretion of GH before puberty - ++ bone elongation
-d/t adenomas (tumour) on pituitary
-rare d/t early detection & to of tumour

Answer 7

Gigantism

Question 8

-increase GH secretion in adulthood
-d/t tumour (pituitary or hypothalamic)
-insidious onset; few seek medical help
-chronic & debilitating
*leads to deformities of hands, feet, jaw, lips, forehead, teeth & nose

Answer 8

Acromegaly

Question 9

Acromegaly affects

Answer 9

-respiration
-vertebral column
-metabolism

Question 10

Thyroxine (T4)?

Answer 10

Major thyroid hormone
-responsible for:
* BP
* BMR & body heat production
* tissue growth & development
* carbohydrate, lipid & protein metabolism

Question 11

Thyroid & thyroid hormones promotes Fxn?

Answer 11

-NS: N development in fetus & infant & N Fxn in adults
-Heart: N Fxn
-MM: development & tone
-Skeletal: growth & maturation
-GI tract: motility, tone & secretion
-Reproductive: female reproductive activity & lactation
-Skin: hydration & secretory activity

Question 12

Goiter (thyroid hypertrophy)?

Answer 12

General manifestation of thyroid

Question 13

Goiter (thyroid hypertrophy) categories

Answer 13

-toxic: severe hyperthryroidism (thhyrotocicosis)
-nontoxic: compensatory hyperplasia & hypertrophy

Question 14

Hypothyroidism may be?

Answer 14

-congenital: cretinism
-acquired: myxedema

Question 15

Myxedema?

Answer 15

Non-pitting, mucus-type edema w/acquired hypothyroidism

Question 16

Most common form of hypothyroidism

Answer 16

Hashimoto’s thyroiditis

Question 17

Hypothyroidism ?

Answer 17

Result of decrease production & secretion of thyroid hormones

Question 18

Causes of hypothyroidism

Answer 18

-thyroidectomy
-radiation tx
-drugs
-increase iodine in diet
-decrease iodine

Question 19

Hashimoto’s thyroiditis

Answer 19

-autoimmune hypothyroidism
-most common form
-female: male = 5:1

Question 20

-a.k.a thyrotoxicosis
-excess delivery of TH to tissues

Answer 20

Hyperthyroidism

Question 21

Causes of hyperthyroidism

Answer 21

-multiinodular Goiter
-adenomas
-overdose of thyroid pills