Lp 66 Flashcards
3 factors affect hormone binding?
-blood levels of hormone
-no. Of receptors on/in cell
-affinity of receptors for hormones
Hormone action:
-decrease no. Of receptors on cell surface
-reduces sensitivity to hormone
Down-regulation
Hormone action:
-increase production of receptors
-target cell becomes more sensitive
Up-regulation
Endocrine dysfunction:
Hypofunction
-under-production &/ or secretion of a hormone
-may be d/t absent or defective glands
Endocrine dysfunction:
Hyperfunction
-++ production &/ or secretion of hormone
-may be d/t: (++ glandular stimulation, hyperplasia of endocrine glands & neoplasms)
3 categorie types of endocrine disorders?
1st disorder: defect w/in gland itself
2nd disorder: n gland but defective levels of stimulating hormones
3rd disorder: hypothalamic dysfunction & leads to both anterior pituitary & target organ being under stimulated.
Pituitary gland hormone:
Anterior pituitary (adenohypophysis) produces?
-tropic hormones
-somatic hormones
Tropic hormones;
-TSH stimulates?
-ACTH stimulates?
-FSH stimulates?
-LH stimulates?
-TSH stimulates thyroid gland to secrete thyroid hormones
-ACTH stimulates secretion of hormones from adrenal cortex
-FSH stimulates sex cell production in ovarian follicles (estrogen production in females)
-LH stimulates production of sex hormones (triggers ovulation in females)
Somatic hormones:
-GH stimulates?
-PRL stimulates?
-GH stimulates growth, mobilizes fats, spares glucose
-PRL stimulates milk production
2 somatic hormones produced by hypothalamus are stored in & secreted by?
Posterior pituitary (neurohypophysis)
-OT stimulates?
-ADH stimulates?
-OT stimulates uterine contractions & milk secretion
-ADH (vasopressin) stimulates kidney to reabsorb water
Hypothalamus and pituitary glands link?
NS & ENDOCRINE SYSTEM
Releasing or inhibiting hormones=
Hypothalamic hormones
Adenohypophysis & hypothalamus linked by?
Portal capillaries
Neurohypophysis & hypothalamus are linked by?
A n tract
