LOCAL ANESTHETICS Flashcards

1
Q

LOCAL ANESTHETICS

A

ESTERS

AMIDES

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2
Q

ESTERS

A

one ‘i’

PROCAINE, NOVOCAINE, CHOLOPROCAINE

BENZOCAINE, BUTAMBEN

COCAINE

TETRACAINE

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3
Q

AMIDES

A

two ‘i’

LIDOCAINE

PRILOCAINE, MEPIVACAINE

BUPIVACAINE, LEVOBUPIVACAINE

ROPIVACAINE

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4
Q

Local anesthetic with the shortest half-life

A

PROCAINE

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5
Q

Local anesthetic with the longest half-life

A

ROPIVACAINE

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6
Q

MOA: Local Anesthetics

A

Block VG Na channels preventing depolarization

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7
Q

Ester with intrinsic sympathomimetic activity causing vasoconstriction. Does not need to be injected with epinephrine.

A

COCAINE

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8
Q

Special SE of Benzocaine and Butamben

A

Methemeglobinemia

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9
Q

TRUE OR FALSE

All local anesthetics are vasodilators except COCAINE.

A

TRUE

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10
Q

Ester used primarily for spinal anesthesia

A

TETRACAINE

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11
Q

Ester causing mood elevation due to action on dopamine receptor

A

COCAINE

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12
Q

Ester used in surgeries involving ear, nose and throat

A

Cocaine

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13
Q

Ester also available as opthalmic solution

A

TETRACAINE

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14
Q

AMIDE used as anti-arrhythmic

A

LIDOCAINE

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15
Q

AMIDE used in dental procedures

A

PRILOCAINE, MEPIVACAINE

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16
Q

Special SE of Lidocaine

A

Transient Neurological Symptoms, Cauda Equina Syndrome

17
Q

Most cardiotoxic out of all LA

A

BUPIVACAINE

LEVOBUPIVACAINE

18
Q

Treatment for cardiotoxicity by Bupivacaine and Levobupivacaine

A

INTRALIPID/LIPOSOMAL FORMS

19
Q

TRUE OR FALSE

Most local anesthetics are weak bases.

A

TRUE

20
Q

TRUE OR FALSE

Alkalinizing the site with bicarbonate will hasten the onset of action of local anesthetics.

A

TRUE

21
Q

LOCAL ANESTHETIC SYSTEMIC TOXICITY (LAST) Treatment

A

Intralipid (Lipid Emulsion Therapy)