LIVER FUNCTION TEST part 1

Question 1

What organ is the largest and most versatile organ in the body?

Answer 1

Liver

Question 2

What is the weight of liver?

Answer 2

1.5 - 1.2 kg

Question 3

What separates the two loves in the liver?

Answer 3

Falciform ligaments

Question 4

carries blood from alimentary tract

Answer 4

Portal vein

Question 5

carries oxygenated blood to the liver

Answer 5

Hepatic artery

Question 6

What is the composition of Liver?

Answer 6

Lobules demarcated by CT septa and
vascular & biliary vessels

Question 7

It is found in the center of the lobule and Parenchymal epithelial cells radiate from the vein.

Answer 7

Central Hepatic Vein

Question 8

blood-carrying vascular channels on either side of the liver cell plates

Answer 8

Sinusoids

Question 9

either endothelial cells or Kupffer cells

Answer 9

Lining cells

Question 10

It is the largest group of fixed macrophages

Answer 10

endothelial cells or Kupffer cells

Question 11

 tissue space between the endothelial cells & hepatocytes

Answer 11

Spice of Disse

Question 12

What fills the Space of Disse?

Answer 12

Interstitial fluid

Question 13

What is the function of Spice of Disse?

Answer 13

It transfer nutrients and waste products from blood occurs

Question 14

 polygonal cells that constitute ~ 60% of the liver mass

Answer 14

Hepatocytes

Question 15

What are the specialized surface of the cell?

Answer 15

 Sinusoidal surface
 Intercellular surface
 Canalicular surface

Question 16

TRUE OR FALSE:
Hepatic parenchymal cells have a underdeveloped organellar substructure.

Answer 16

FALSE ; developed

Question 17

energy generation

Answer 17

Mitochondria

Question 18

What is the other name of Lysosomes?

Answer 18

Hydrolytic enzymes

Question 19

degradative functions

Answer 19

Lysosomes

Question 20

site of many functions: drug metabolism & bile acid SYNTHESIS

Answer 20

Endoplasmic reticulum

Question 21

tubules & vesicles

Answer 21

Smooth ER

Question 22

This organ function as: bilirubin conjugation, drug detoxification & cholesterol synthesis

Answer 22

Smooth ER

Question 23

lamellar profile with ribosomes

Answer 23

Rough ER

Question 24

 synthesis of specific proteins (e.g. albumin, coagulation factors)

Answer 24

Rough ER

Question 25

It functions as the “packaging process” of the cell

Answer 25

Golgi complex

Question 26

produces lipoproteins (VLDL) ; Glycoprotein synthesis

Answer 26

Golgi Complex

Question 27

maintain cell shape and provide contractile force

Answer 27

Microtubules and Microfilaments

Question 28

Receives, processes & stores materials absorbed from the digestive tract

Answer 28

Microtubules and Microfilaments

Question 29

What are the materials that are absorbed and stored from the DT?

Answer 29

 amino acids
 CHO
 fatty acids
 cholesterol

Question 30

multiple plasma proteins

Answer 30

Synthesis

Question 31

Main organ of detoxification
Major site of catabolism of hormones

Answer 31

Microtubules and Microfilaments

Question 32

These tests are done for liver function test

Answer 32

test for the proteins, bilirubin, ammonia and enzymes (ALT,AST, GTT, AGPT, SGOT)

Question 33

What are the factors to be considered in doing Liver Function Tests?

Answer 33

Sensitivity
Specificity
Selectivity