KIDNEY FUNCTION TEST part 1 Flashcards
It is a pair of organs located at the retroperitoneal space.
KIDNEY
What function eliminates wastes and excess inorganic substances via urine formation?
EXCRETORY FUNCTION
What role does Regulatory Function does?
HOMEOSTASIS
What function is the mechanism of differential reabsorption and secretion in the renal tube?
REGULATORY FUNCTION
What is the function of 1° endocrine function?
Production of hormones
It is the site of degradation of insulin, glucagon and aldosterone.
2° endocrine function
What do you call the substances that are derived from the catabolism of proteins and nucleic acids but not considered as protein but are considered as “waste products” and contains nitrogen?
NPN (Nonprotein Nitrogenous Compound)
What sample is/are most often used to assess Renal function?
Urea
Uric Acid
Creatinine
What sample is used for Liver function?
Ammonia
What are the 2-steps in Total NPN Methodology?
Kjeldahl digestion
Measurement of ammonia formed
It is a process wherein Nitrogen in a pff is converted into NH3 using H2SO4
Kjeldahl digestion
Under Kjeldahl digestion, pff is converted into NH3 using what substance?
H2SO4
What is the product and the color of the product of Nesslerization?
Dimercuric Ammonuim Iodide
Yellow - Brown color
In nesslerization, NH3 reacts with Nessler’s reagent. What are these reagents?
Double Iodide Salt of Potassium and Mercury.
Under Berthelot method, reacts with _______________ and _____________.
Phenol
Alkaline hypochlorite
This substance chlorinates ammonia to monochloramine.
Sodium Hypochlorite
What is the catalyst of Berthelot method?
Sodium Nitroprusside
What is the product of Berthelot method?
Indophenol blue
At what pH is Berthelot method maintained with the Na Nitroprusside acting as a catalyst?
Alkaline pH (>10)
Under Berthelot method, there is a modification by Searcy. Now, what is used instead of Phenol?
Salicylic acid
The combination of NH3, a-ketoglurate and NADH will yield a product of?
Glumate and NAD
In monitoring consumption of NH3, what is the catalyst present?
Glutamate Dehydrogenase
Monitoring consumption of NH3 is measured at what wavelength?
340nm
This substance is the major N-containing product of protein metabolism wherein it accounts for almost 45% of it.
UREA
Urea is produced through what cycle?
Krebs-Henseleit cycle
TRUE OR FLASE:
Urea is 40% reabsorbed, small amount is excreted through sweat and degraded by the bacteria in the small intestines.
TRUE
Where is Urea freely filtered?
Glomerulus
In Renal Handling of Urea, it is dependent on?
Urine flow rate
The clearance of Urea us proportional to the GFR.
Rapid flow rate
Why is BUN not reliable for monitoring renal function?
- It is affected by the body’s state of hydration
- It is largely affected by protein intake and catabolism
- Large amount is reabsorbed in renal tubules
