List #7 Flashcards
1
Q
myelin
A
-lipid material that forms a sheath like covering around some axons
2
Q
axonal transport
A
- movement occurs in both directions between the cell body and the ends of the axon.
- enzymes required for neurotransmitter synthesis are produced in the cell body and transported to the axon terminals.
3
Q
membrane potential
A
- The potential difference across the cell membrane(measured in millivolts)
4
Q
resting membrane potential
A
- one that is not sending impulses or responding to other neurons(-70 millivolts)
5
Q
action potential
A
- a rapid change in the membrane potential, first in a positive direction, then in a negative direction, returning to the resting potential
- all or nothing
- regenerative
6
Q
depolarization
A
- if the membrane becomes more positive than the resting potential
- can be caused by Sodium entering
- means the threshold is lowered for an action potential
7
Q
hyperpolarization
A
- if the membrane potential becomes more negative than the resting potential
- the threshold is raised
8
Q
refractory period
A
- During the absolute refractory period which lasts about 1/1,000 of a second, the axon’s voltage-gated sodium channels are temporarily not responsive at all, and the axon cannot be stimulated.
- Then the relative refractory period follows, as the membrane reestablishes its resting potential.
9
Q
saltatory conduction
A
- Action potentials appear to jump form node to node
- conduction on myelinated axons is many times faster than conduction on unmyelinated axons
10
Q
synaptic potentials
A
- enable one neuron the affect another
- EPSP/IPSP
- graded
- non-regenerative
11
Q
EPSP
A
- A neuro transmitter binds to a post-synaptic receptor and opens sodium ion channels, the ions diffuse inward, depolarizing the membrane possibly triggering an action potential.
- lasts for about 15 milliseconds
- Depolarizing
- Glumate
12
Q
IPSP
A
- A different neurotransmitter binds other receptors and increases membrane permeability to potassium ions, these ions diffuse outward hyperpolarizing the membrane
- Hyperpolarizing
- GABA
13
Q
monoamines
A
- modified amino acids
14
Q
neuropeptides
A
- These peptides act as neurotransmitters or a neuromodulators, which are substances that alter a neurons response to a neurotransmitter or block the release of a neurotransmitter.
- enkephalins and endorphins
15
Q
enkephalins
A
-Generally inhibitory; reduce pain by inhibiting substance P release (CNS)
16
Q
glutamic acid (glutamate)
A
-Generally excitatory (CNS)
17
Q
monoamine oxidase
A
- Inactivates the monoamine neurotransmitters epinephrine and norepinephrine after reuptake
- It is found in the mitochondria in the synaptic knob
18
Q
serotonin
A
-Primarily inhibitory; leads to sleepiness; action is blocked by LSD, enhanced by selective serotonin reuptake inhibitor antidepressant drugs (CNS)