Lipid 2 part 2 Flashcards

1
Q
A
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2
Q

carry TG

A

CM and VLDL

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3
Q

CE carried by

A

LDL

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4
Q

CE and phospholipids

A

carried by hdl

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5
Q

how to get rid of cholesterol

A

—>liver–> bile salts—> SI—> secreted in feces

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6
Q

– plasma enzyme (in the bloodstream)

A

LPL

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7
Q

breaks down TG→FA

A

LPL

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8
Q

activated as cofactor APO-C (CM and VLDL)

A

LPL

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9
Q

Lecithin cholesterol acyl transferase (LCAT

A

acyl chains on lecithin and transfers to cholesterol to make a CE

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10
Q

– activated by cofactor APO-A (HDL)

A

Lecithin cholesterol acyl transferase (LCAT

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11
Q

activated by cofactor APO-A (HDL) in the bloodstream

A

LCAT

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12
Q

takes acyl Co-A and cholesterol inside of liver cells

A

ACAT

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13
Q

in liver cell

A

ACAT

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14
Q

HMG Co-A Reductase

A

makes cholesterol the rate limiting step of cholesterol biosynthesis

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15
Q

Intracellular enzymes

A

HMG Co-A Reductase ACAT

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16
Q

in blood stream

A

LDL

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17
Q

LPL cofactor

A

apo C

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18
Q

APO-B –

A

ligand for LDL receptor

19
Q

APO-A –

A

LCAT cofactor

20
Q

APO-A –

A

ligand for 2 receptors/transporters ABCA1&SRB1

21
Q

lipoprotein

A

phospholipid with apoprotein croplet containing TG and CE

22
Q

apo protein

A

stabilize droplet and have act enzyme and transporters

23
Q

chylomicron

A

made from interstinal mucosal cell

24
Q

ACAT

A

Chol-> CE in int. mucosal cell

25
apo protein C and E
CM
26
LPL
TG to FA in CM and transfers to adipose cels
27
once in Adipose cell
FA made back to TG
28
after CM delivers TG to adipose cell
it delivers CE to Liver
29
CM binds to liver thru
APo E
30
Liver make
TG from F CE FROM CHOL bile from Chol
31
VLDL
come from Liver
32
VLDL
apo B and C TG and CE
33
go to adipose tissues
LDL and VLDL
34
LPL acts in
LDL and VLDL to make FA and deliver to adipose tissue
35
after coming from adipose tissue
LDL is formed from VLDL
36
only hase apo B
LDL after adipose tissue
37
endocytosis
of LDL particle on Peripheal cell(CE in)
38
adrenal gland recieves
LDL and takes in CE to form Chol(make steroid hormones)
39
tf all cells have ability to make cholesterol
T but only liver and adrenal cells do
40
Liver secretes APO a
to another peripheal cell
41
ABCA1
transporter for APO A
42
Chol and phospholipid combined
with APO A1 to make HDL
43
SBR1
on liver and recieves HDL(with chol and phospholipid)