signal trans 4 part 2

Question 2

tf in cholera there is minimum loss of Na and water in intestines

Answer 2

F excessive

Question 3

pertusssis toxin

Answer 3

transfer ADP ribose to Cys on alpha subunit of Gi

Gi cant bing AC and cant inh

Question 4

inc Pka and camp exist in

Answer 4

cholera and pertussis

Question 5

High insulin; low glucose (seizures)

High histamine; low pressure (shock)

Answer 5

Pertussis

Question 6

TF hormone levels not affected in pertussis

Answer 6

F affected

Question 7

termination of camp

Answer 7

pde converts it to 5’ amp

Question 8

GC

Answer 8

converts GTP to cGMP

Question 9

bind ssoluble GC on a heme

Answer 9

NO

Question 10

binds to membrane ass GC

Answer 10

ANF

Question 11

cGMP act

Answer 11

PKG

Question 12

cGMP term to

Answer 12

5 gmp by cGMP Phosphodiesterase

Question 13

Pi PE PC

Answer 13

polar head group of phosphpholipid

Question 14

PIP2

Answer 14

Major Substrate for Producing Second Messengers

Question 15

Phosphoinositide-4-Kinase

Answer 15

convert PI to PIP

Question 16

PIP converted to PIP2 by

Answer 16

Phosphoinositide-5-Kinase

Question 17

Activator of Ca2+ release from endoplasmic reticulum

Answer 17

IP3

Question 18

phospholipase C

Answer 18

breaks PIP2 into DAG and IP3

Question 19

DAG

Answer 19

Membrane bound

Question 20

Activator of protein kinase C (PKC)

Answer 20

DAG

Question 21

phsopholipase D

Answer 21

breaks PC into phosphatidic acid and choline

(1st step of DAG generation)

Question 22

PAP

Answer 22

break phosphatidic acid ito DAG and PO4

(2nd step)

Question 25

IP3 act

Answer 25

ip3sensitive channels to let out Ca

Ca bind protein kinase C which binds DAG (membrane) which phos substrates

Question 26

Precursor for production of eicosanoids

Answer 26

Arachidonic acid (AA) –

Question 27

phosphlipase A2

Answer 27

breaks PIP2 into AA(membrane bound) and

Question 28

PI

Answer 28

only has PO4 on 1 position

Question 29

PIP

Answer 29

PO4 on 4 position

Question 30

PIP2

Answer 30

po4 on 1,4,5 position

Question 31

tf phosphatase can convert PIP3 to PIP2 to PIP1 to PI

Answer 31

T

Question 32

PIP3

Answer 32

Activator of kinases recruited to membrane

Question 33

PI 3 kinase

Answer 33

puts po4 on 3 position converts PIP2 to PIP3

Question 35

exist in cytoplasm

Answer 35

camp cgmp ip3

Question 36

membrane

Answer 36

DAG AA PIP3

Question 37

tf IP3 and PIP3 use PIP2 as a source

Answer 37

T

Question 38

AA and DAG

Answer 38

use PC and PE as a source

Question 39

uses PI PIP PIP2 as sources

Answer 39

AA

Question 40

tf dag can use PIP2 as source

Answer 40

T

Question 41

ATP;GTP as source

Answer 41

camp; cgmp

Question 43

Forms eicosanoids

Answer 43

AA

Question 44

Activates PKB, PDK1

Answer 44

PIP3

Question 45

act. pkg;pkc

Answer 45

cGMP;DAG

Question 46

act pka

Answer 46

camp

Question 47

release Ca from ER

Answer 47

IP3

Question 48

effector AC ; GC

Answer 48

camp; cgmp

Question 49

Pla2 is effector enzyme for

Answer 49

AA

Question 50

pi 3k effector enzyme for

Answer 50

PIP3

Question 51

PLC is effector nzyme for

Answer 51

IP3 and DAG

Question 52

PLD/PAP effector enzyme fore

Answer 52

DAG

Question 53

GC effector enzyme for

Answer 53

cGMP