Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

biochem block3 part 2 > CT 2 part 2 > Flashcards

CT 2 part 2 Flashcards

1
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

binds ECM and transmembrane proteins

A

fibronectins and laminins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

linker protein-mediated “communication”.

A

fibronectins and laminins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

alpha beta subunit

A

integrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

tf

Cells can have 1 integrin receptors that link the cell to only one component of the extracellular matrix.

A

Cells can have multiple integrin receptors that link the cell to more than one component of the extracellular matrix.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The ——/—– sequence on the linker proteins binds specifically to the integrin receptors.

A

RGD/RGDS sequence on the linker proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Activation of integrins can lead to their — and —— of focal adhesions

A

Activation of integrins can lead to their clustering and formation of focal adhesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

C terminus of alpha and beta subunits of integrin

A

located in cytoplams

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

alpha subunit split into 2 segments

A

and linked together by disulfide linkage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

disulfide rich repeats exist in

A

beta subunit of integrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

integrin binds to actin on

A

cytoskeleton side

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

out to in signal of integrin

A

ligand binds from ECM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Out to in signal in integrin

A

cell polarity

surviva;

proliferation

cytoskeletal structure

gene expression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Talin

A

involved in in to out signaling with integrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

cell migration

cell adhesion

ECM assembly

A

In to Out signaling with integrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

regulation of the extracellular binding activity of a cell’s integrins from within.

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

collagen

A

GP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Chemotaxis

A

Collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

(major stress-bearing component

A

Colagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Collagens form —– fibers with high —- strength; hold cells together in discrete units.

A

Collagens form insoluble fibers with high tensile strength; hold cells together in discrete units.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

By weight, —- of the protein in vertebrates is collagen

A

By weight, 1/4 of the protein in vertebrates is collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

cornea cartiledge

A

high percent collagen by weight

64 50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

highest percent collagen by weight

A

skin 74

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

liver lung

A

small percent colagen by wieght

4 and 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
cOrtical Bone aOrta
23% 10-24% % collagen by wieght
27
after fibroblast make polypeptide system
OH and glycosylation occurs(collagen)
28
Secretion of procolllagen is followed by
hydrolysis of peptide bond to form tropocollagen
29
self assembly of tropocolagen to form
collagen fibers
30
crosslink in colagen fiber leads to
mature collagen fiber
31
tf collagen fber is made in between procolagen and tropocollagen
F after tropocollagen
32
tf collagenis product of few genes and few types
F over 40 genes 28 types
33
types 2 and 3 collagen
homotrimers
34
collagen 1,4,5
heterotrimers
35
polppetide in collegen
alpha
36
placenta skin
type 5 collagen
37
basment membrane
type 4 collagen
38
cartildge IVD
collagen 2
39
skin tendon
type 1 collagen
40
bone dentin
type 1 collagen
41
BV uterus reticular fibers
type 3 collagen
42
triple helical rod
collagen
43
Remarkably strong Forms an insoluble fiber with high tensile strength
collagen
44
collagen
3000 Å long and 15 Å diameter
45
1/3 of the amino acids in collagen
Glycine
46
Proline 4-Hydroxyproline (Hyp) 3-Hydroxyproline (Hyp)
collagen
47
5-Hydroxylysine
collagen
48
tf collgen has Charged (---) amino acids
F Charged (positive) amino acids
49
highest component in collagen and elastin
Gly
50
5 hydroxylysine
not present in elastin present in collagn
51
desmosine and isodesmosine not in
collagen
52
collagen primary structure
glu X Y
53
X
Proline
54
Y
hydroxyproline
55
polar basic AA
also in collagen
56
X
proline
57
tf 3 hydroxylysine is in collagen
F 5 hydroxylysine
58
Y
hydroxyproline
59
60
secondary structure of collagen
tropocollagen with left handed helical structure
61
type 2 trans helix
2nd and tert structure of Collagen
62
quat structure
type 2 transhelix twist around each other to form right handed helix(superhelix)
63
triple helix of tropocollagen
has glycine in the middle

biochem block3 part 2 (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions