Leukocytes Flashcards
Maturation time
14 days
Diameter: 14-20 um
Myeloblast
Diameter: 16-25 um
Promyelocyte
Diameter: 15-18 um
Myelocyte
Diameter: 14-16 um
Metamyelocyte
Diameter: 9-15 um
Band/Stab
Diameter: 9-15 um
Segmented Neutrophil
- High N:C ratio (8:1 to 4:1)
- Slightly basophilic cytoplasm, fine nuclear chromatin
- 2-4 visible nucleoli
Myeloblast
- The nucleus is round to oval and is often eccentric.
- A paranuclear halo or “hof” is usually seen
- The cytoplasm is evenly basophilic
Promyelocyte
The cytoplasm is evenly basophilic
Promyelocyte
Last stage capable of cell division
Myelocyte
Nucleus has more heterochromatin; cytoplasm is more lavender-pink than blue
Myelocyte
Start of Synthesis of Secondary Granules
Myelocyte
Start of Synthesis of Tertiary Granules
Metamyelocyte
The cytoplasm contains very little residual RNA (little or no basophilia)
Metamyelocyte
Indented nucleus (kidney bean-shaped or peanut shaped)
Metamyelocyte
Youngest stage to appear normally in peripheral circulation
Band Neutrophil
The nucleus is highly clumped; indentation exceeds one
half the diameter of the nucleus
Band Neutrophil
Secretory granules / secretory vesicles are formed
Band Neutrophil
Secretory granules continue to be formed
Segmented Neutrophil
Presence of 3-5 nuclear lobes connected by thread-like filaments
Segmented Neutrophil
T or F
Myeloblast, Promyelocyte, Myelocyte are stages capable of mitosis
T
Appearance of Granules:
PROMYELOCYTE
Primary granules (Non-specific Granules)
Appearance of Granules:
MYELOCYTE
Secondary granules (Specific Granules)
Appearance of Granules:
METAMYELOCYTE
Tertiary Granules
Appearance of Granules:
BAND / STAB CELL
Secretory Granules
term for < 3 lobes
hyposegmented
term for > 3 lobes
hypersegmented