BONE MARROW EXAMINATION Flashcards

1
Q

Before BM collection (________), blood is collected for CBC with blood film
examination

A

<24 hours

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2
Q

Site of collection for BM Exam:

A

POSTERIOR ILIAC CREST of the pelvis (Preferred)
Sternum
Anterior medial surface of the tibia

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3
Q

Types of needles that are used for collection for BM Exam:

A

Jamshidi biopsy needle
Westerman-Jensen biopsy needle
University of Illinois aspiration needle
Snarecoil biopsy needle

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4
Q

Cytologic assessment

A

BM ASPIRATE

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5
Q

Cell morphology observation

A

BM ASPIRATE

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6
Q

Differential count (300-1000 cells)

A

BM ASPIRATE

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7
Q

BM architecture

A

BM CORE BIOPSY

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8
Q

BM cellularity (cell to fat ratio)

A

BM CORE BIOPSY

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9
Q

Detection of focal lesions

A

BM CORE BIOPSY

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10
Q

Wright stain

A

BM CORE ASPIRATE

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11
Q

Prussian blue

A

BM CORE ASPIRATE

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12
Q

determines iron stores

A

Prussian blue

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13
Q

Cytochemical stain

A

BM CORE ASPIRATE

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14
Q

H&E

A

BM CORE BIOPSY

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15
Q

BONE MARROW CELLULARITY:
For children:

A

80% cellularity

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16
Q

BONE MARROW CELLULARITY:
For ages 30-70 years old:

A

50% cellularity

17
Q

BONE MARROW CELLULARITY:
For ages > 70 years old:

A

(100% - patient age) +10%

18
Q

↓ cells and ↑ fat

A

Hypocellular/Hypoplastic

19
Q

↑ cells and ↓ fat

A

Hypercellular/Hyperplastic

20
Q

MYELOID TO ERYTHROID RATIO
Normal:

A

1.5-3.3 : 1

21
Q

MYELOID TO ERYTHROID RATIO
Infections:

A

Increased

22
Q

MYELOID TO ERYTHROID RATIO
Leukemia:

A

Increased

23
Q

MYELOID TO ERYTHROID RATIO
Depression of Leukopoiesis:

A

Decreased

24
Q

OTHER DEFINITIVE TESTS ON BM SAMPLES
Used in classifying Leukemia & Lymphoma:

A

Cytochemical studies
Cytogenetic studies
Flow cytometry