LEUKEMIA Flashcards

1
Q

Refers to the rapid, clonal proliferation in the bone marrow of lymphoid or myeloid progenitor cells known as lymphoblasts and myeloblasts

A

LEUKEMIA

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2
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Acute
Predominant Cell Type:

A

Precursors/ Blasts

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3
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Chronic
Predominant Cell Type:

A

Mature

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4
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Acute
Onset:

A

Sudden

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5
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Chronic
Onset:

A

Insidious

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6
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Acute
Symptoms:

A

Fever
Fatigue
Bleeding

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7
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Chronic
Symptoms:

A

Variable
Non-specific

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8
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Acute
Progression w/o treatment:

A

Rapid; weeks to month

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9
Q

CYTOGENETIC ABNORMALITIES IN LEUKEMIA:
Chronic
Progression w/o treatment:

A

Slow; months to years

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10
Q

Based on Cell morphology and cytochemical staining

A

French-American-British (FAB) System

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11
Q

Emphasized molecular and cytogenetic abnormalities

A

World Health Organization (WHO) System

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