ERYTHROCYTE SEDIMENTATION RATE Flashcards
Measures the degree of settling of RBCs in plasma in anticoagulated whole blood
ERYTHROCYTE SEDIMENTATION RATE
is the distance in millimeters that the RBCs fall in 1 hour
ERYTHROCYTE SEDIMENTATION RATE
ESR is non-specific measurement used to detect and monitor ________
Inflammatory responses
Most important factor affecting ESR:
Fibrinogen Factor
↑ Fibrinogen (inflammation) =
↑ ESR
Anticoagulant for ESR
EDTA/ 0.105m Na citrate
- Length = 300 mm
- Ext bore diameter = 5.5 mm
- Int bore diameter = 2.5 mm
- Graduation – 0-200 mm
Westergren Method
- Length = 115 mm
- Int bore diameter = 3 mm
- Graduation – 0-100 mm
Wintrobe Method
Acute/Chronic infections
Increased
Multiple Myeloma / Waldenstrom’s
Increased
Hyperfibrinogenemia
Increased
Anemia, Macrocytosis
Increased
AMI, ESRD, RA, DM, Gout
Increased
Neoplastic disease
Increased
Pregnancy, menstruation
Increased
Polycythemia / Pancytosis
Decreased
Poikilocytes
Decreased
Microcytosis
Decreased
Hypofibrinogenemia
Decreased
Hypogammaglobulinemia
Decreased
Newborn
Decreased
MECHANICAL/TECHNICAL FACTORS:
High temperature, tilted ESR tube, vibration:
Falsely High ESR
3o tilt = up to _____ error
30%
Low temperature, old sample, bubbles in ESR tube
Falsely low ESR
ESR Temperature: 20-25oC; test should be performed within _____ after blood
collection if kept at room temperature
4 hours
