Lesson 10 Flashcards

1
Q

The chemicals (drugs) used to treat diseases are referred to as

A

Chemotherapeutic agents

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2
Q

Any drug used to treat diseases

A

Chemotherapeutic agents

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3
Q

The chemotherapeutic agents used to treat infectious disease

A

Antimicrobial agents

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4
Q

The “Father of Chemotherapy”

A

Paul Erhlich

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5
Q

Proved effective in treating syphilis

A

Salvarsan

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6
Q

Salvarsan is also known as

A

Compound 606

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7
Q

Drugs used to treat bacterial disease

A

Antibacterial agents

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8
Q

Drugs uswd to treat virus

A

Antiviral agent

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9
Q

A substance produced by a microorganism that is effective in killing or inhibiting the growth of other microorganisms

A

Antibiotic

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10
Q

Are all antibiotics an antimicrobial agents?

A

Yes

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11
Q

Are all antimicrobial agents an antibiotic

A

No

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12
Q

Example of antibiotics produced by moulds

A

Penicillin and Cephalosporin

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13
Q

Inhibit the production of folic acid in those bacteria that require p-aminobenzoic acid

A

Sulfonamide drugs

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14
Q

Inhibit growth of bacteria

A

Static

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15
Q

They kill EITHER gram negative or positive bacteria

A

Narrow spectrum antibiotics

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16
Q

They kill BOTH gram negative or positive bacteria

A

Broad Spectrum Antibiotics

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17
Q

It destroys gram positive bacteria

A

Vancomycij

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18
Q

They destroy gram negative bacteria

A

Colistin and nalidixic acid

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19
Q

Major categories of antibacterial agents

A

PCTAMF
Penicillin
Cephalosporin
Tetracycline
Aminoglycosides
Macrolides
Fluoroquinolones

20
Q

Referred to a B-lactam drugs

A

Penicillin

21
Q

Molecular structure includes a four sided ring structure known as

A

B-lactam ring

22
Q

Clostridium perfringes

A

Anaerobic bacteria

23
Q

Treponema pallidum

A

Spirochetes

24
Q

Staphylococcus aureus, streptococcus pneumoniae

A

Gram positive cocci

25
Q

Are B-lactam antibiotics, and like penicillin are produced by moulds

A

Cephalosporin

26
Q

What generation:
Active against gram positive bacteria

A

First generation

27
Q

What generation:
Active against gram negative bacteria

A

Second generation

28
Q

What generation:
Even greater activity against gram negative bacteria

A

Third generation

29
Q

Active against both positive and negative bacteria

A

Fourth gen

30
Q

Broad spectrum drugs that exert their effect by targeting bacterial ribosomes

A

Tetracycline

31
Q

Broad spectrum drugs that inhibit bacterial protein synthesis

A

Aminoglycosides

32
Q

Inhibit protein synthesis

A

Macrolides

33
Q

Are effective against members of the family Enterobactericiae and P. Aeriginosa

A

Fluoroquinolones

34
Q

Antibiotic against chalmydias, mycoplasmas, rickettsia, vibro cholerae, and spirochette

A

Tetracycline

35
Q

Antibiotics effective against gram negative

A

Aminoglycosidwz

36
Q

The use of two or more drugs simultaneously to kill all the pathogens

A

Multidrug therapy

37
Q

Multiresistsnt strain of M. Tuberculosis

A

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol

38
Q

The use of two antimicrobial agents to treat an infectious disease produces a degree of pathogens

A

Synergism

39
Q

When the use of two drugs produces an extent of pathogen killing

A

Antagonism

40
Q

The first antiviral agent effective against HIV

A

zidovudine

41
Q

Refers to an organism that is resistant to only one antimicrobial agent

A

Superbug

42
Q

Resistant to antistaphylococcal drugs except vancomycin

A

MRSA AND MRSE

43
Q

Have developed resistance to the usual dosages of vancomycin

A

VISA

44
Q

Strains have been isolated that are resistant to even the highest practical doses of vancomycin

A

VRSQ

45
Q

Strains are resistant to most anti-enterococcal drugs

A

VRE