Lesson 10 Flashcards

1
Q

The chemicals (drugs) used to treat diseases are referred to as

A

Chemotherapeutic agents

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2
Q

Any drug used to treat diseases

A

Chemotherapeutic agents

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3
Q

The chemotherapeutic agents used to treat infectious disease

A

Antimicrobial agents

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4
Q

The “Father of Chemotherapy”

A

Paul Erhlich

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5
Q

Proved effective in treating syphilis

A

Salvarsan

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6
Q

Salvarsan is also known as

A

Compound 606

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7
Q

Drugs used to treat bacterial disease

A

Antibacterial agents

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8
Q

Drugs uswd to treat virus

A

Antiviral agent

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9
Q

A substance produced by a microorganism that is effective in killing or inhibiting the growth of other microorganisms

A

Antibiotic

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10
Q

Are all antibiotics an antimicrobial agents?

A

Yes

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11
Q

Are all antimicrobial agents an antibiotic

A

No

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12
Q

Example of antibiotics produced by moulds

A

Penicillin and Cephalosporin

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13
Q

Inhibit the production of folic acid in those bacteria that require p-aminobenzoic acid

A

Sulfonamide drugs

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14
Q

Inhibit growth of bacteria

A

Static

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15
Q

They kill EITHER gram negative or positive bacteria

A

Narrow spectrum antibiotics

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16
Q

They kill BOTH gram negative or positive bacteria

A

Broad Spectrum Antibiotics

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17
Q

It destroys gram positive bacteria

A

Vancomycij

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18
Q

They destroy gram negative bacteria

A

Colistin and nalidixic acid

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19
Q

Major categories of antibacterial agents

A

PCTAMF
Penicillin
Cephalosporin
Tetracycline
Aminoglycosides
Macrolides
Fluoroquinolones

20
Q

Referred to a B-lactam drugs

A

Penicillin

21
Q

Molecular structure includes a four sided ring structure known as

A

B-lactam ring

22
Q

Clostridium perfringes

A

Anaerobic bacteria

23
Q

Treponema pallidum

A

Spirochetes

24
Q

Staphylococcus aureus, streptococcus pneumoniae

A

Gram positive cocci

25
Are B-lactam antibiotics, and like penicillin are produced by moulds
Cephalosporin
26
What generation: Active against gram positive bacteria
First generation
27
What generation: Active against gram negative bacteria
Second generation
28
What generation: Even greater activity against gram negative bacteria
Third generation
29
Active against both positive and negative bacteria
Fourth gen
30
Broad spectrum drugs that exert their effect by targeting bacterial ribosomes
Tetracycline
31
Broad spectrum drugs that inhibit bacterial protein synthesis
Aminoglycosides
32
Inhibit protein synthesis
Macrolides
33
Are effective against members of the family Enterobactericiae and P. Aeriginosa
Fluoroquinolones
34
Antibiotic against chalmydias, mycoplasmas, rickettsia, vibro cholerae, and spirochette
Tetracycline
35
Antibiotics effective against gram negative
Aminoglycosidwz
36
The use of two or more drugs simultaneously to kill all the pathogens
Multidrug therapy
37
Multiresistsnt strain of M. Tuberculosis
Rifampicin Isoniazid Pyrazinamide Ethambutol
38
The use of two antimicrobial agents to treat an infectious disease produces a degree of pathogens
Synergism
39
When the use of two drugs produces an extent of pathogen killing
Antagonism
40
The first antiviral agent effective against HIV
zidovudine
41
Refers to an organism that is resistant to only one antimicrobial agent
Superbug
42
Resistant to antistaphylococcal drugs except vancomycin
MRSA AND MRSE
43
Have developed resistance to the usual dosages of vancomycin
VISA
44
Strains have been isolated that are resistant to even the highest practical doses of vancomycin
VRSQ
45
Strains are resistant to most anti-enterococcal drugs
VRE