Lecture 49 Clearance

Question 1

IF a substance is not excreted in the urine, what is its clearance?

Answer 1

it is 0, glucose or albumin

Question 2

If the substance is filtered and not reabsorbed or secreted the urine its clearance is the same as _______

Answer 2

GFR inulin

Question 3

if the substance undergoes net reabsorption its clearance will be less than that of inulin

Answer 3

Na, Urea, Chlorine

Question 4

If the substance undergoes net secretion its clearance will be greater than inulin

Answer 4

PAH

Question 5

If excretion < filtered load there is net ________ of a substance

Answer 5

reabsorption

Question 6

If excretion > filtered load then there is net ________ of a substance.

Answer 6

secretion

Question 7

GFR is _______ related to plasma creatinine

Answer 7

inversely

Question 8

Clearance of ______ = renal plasma flow (RPF)

Answer 8

para amino hippurate,

it is a freely filtered organic anion.
avidly secreted by peritubular capillaries into the proximal tubule.

Question 9

FeNa <1% suggest _____ causes of acute renal failure

FeNa> 2% suggests ________

Answer 9

prerenal

acute tubular necrosis