Lecture 46 Distribution of Body Fluids

Question 1

What is the total body water equation?

Answer 1

0.6 * ( body weight)

males= 60% weight in kg
females= 55% weight in kg
1kg=2.2lbs

Question 2

what are the major cations and anions in the ICF?

Answer 2

K+ Mg+

proteins and organic phosphate PO4-

Question 3

what are the major ECF cations and anions?

Answer 3

Na+ and CL, HCO3

Question 4

what is the ECF ( extracellular fluid equation)?

Answer 4

ECF= Interstitial fluid (ISF) + Plasma volume (PV)

Or

ISF= ECF -PV

Question 5

what is the ICF and ECF equation?

Answer 5

ICF= 2/3 TBW.
( total body water)

ECF=1/3 TBW

Question 6

what is the equation for blood volume?

Answer 6

BV= (PV)/ (1-Hc)

Pv= plasma volume 
Hc= hematocrit

Question 7

ISW equation:

plasma equation:

Answer 7

ISW= 75%ECF

Plasma=25%ECF

Question 8

what substances are useful to measure total body water because they distribute around all body compartments?

Answer 8

isotopic water (D20)
titrated water (THO)
Antipyrine

Question 9

what substances remain in the ECF and can’t cross the cell membranes, but they’re useful in measuring ECF?

Answer 9

Sulfate, mannitol, and inulin

Question 10

What substances are useful in measuring plasma volume ( PV)?

Answer 10

Radioactive albumin

Evans Blue

Question 11

what is the ICF equation?

Answer 11

ICF=TBW - ECF

Question 12

In a dye technique, a known amount of dye is injected and equilibrated, then the concentration of the dye is measured in plasma. Then the volumes are calculated.

what is the equation for this experiment? compartment volume

Answer 12

compartment volume= amount injected- amount excreted/ ( concentration in plasma)

see slide 10 and redo example

then use the answer and compare it to high weight ex:

40/60= 66%; normal is between 50-70%

Question 13

Any changes in volume will 1st affect the __________ volume

The change in volume of ICF occurs only by changes in _____________

Answer 13

ECF

ECF osmolarity

Question 14

what is the equation for plasma osmolarity?

Answer 14

2XNa + glucose / (18+BUN)/2.8

Question 15

Diarrhea is

isoosomotic, hyperosmotic, hypo osmotic?

Answer 15

isoosmotic

Question 16

If you lose a lot of blood are you

isoosomotic, hyperosmotic, hypo osmotic?

Answer 16

isoosmotic

Question 17

a marathon runner drinks a lot of water are you isoosomotic, hyperosmotic, hypo osmotic?

Answer 17

hypoosmotic

Question 18

if you are hiking in the mountains and you have no food and water for two days
isoosomotic, hyperosmotic, hypo osmotic

Answer 18

hyperosmotic

Question 19

infusion of 0.9% NaCl cus of kidney stones

isoosomotic, hyperosmotic, hypo osmotic

Answer 19

isoosmotic

Question 20

adrenal insufficiency

isoosomotic, hyperosmotic, hypo osmotic

Answer 20

hyposmotic

Question 21

3% Nacl

isoosomotic, hyperosmotic, hypo osmotic

Answer 21

no answer?

Question 22

oat cell carcinoma excess ADH SIADH

isoosomotic, hyperosmotic, hypo osmotic

Answer 22

hypoosmotic

Question 23

0.45% saline

5% dextrose in 0.45% saline

Answer 23

hypotonic/ hypotonic

Question 24

0.9% SALINE, RINGERS SOLUTION, 5% dextrose in 0.9% saline

Answer 24

isotonic solution

Question 25

3% saline

Answer 25

hyperotonic